SLC12A1 抗体
-
- 抗原 See all SLC12A1 抗体
- SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
-
适用
- 大鼠, 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SLC12A1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human SLC12A1
- 亚型
- IgG
- Top Product
- Discover our top product SLC12A1 Primary Antibody
-
-
- 应用备注
- WB 1:500 - 1:2000
- 限制
- 仅限研究用
-
- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
- 别名
- SLC12A1 (SLC12A1 产品)
- 别名
- slc12a1 antibody, SLC12A1 antibody, DKFZp469A2020 antibody, BSC1 antibody, NKCC2 antibody, Nkcc2 antibody, AI788571 antibody, D630042G03Rik antibody, mBSC1 antibody, urehr3 antibody, si:ch211-220f12.1 antibody, solute carrier family 12 member 1 antibody, solute carrier family 12, member 1 antibody, si:ch211-220f12.1 antibody, SLC12A1 antibody, Slc12a1 antibody
- 背景
-
Synonyms: BSC1,Bumetanide sensitive sodium 3,Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2,Kidney specific Na K Cl symporter,Kidney-specific Na-K-Cl symporter,MGC48843,Na K 2Cl cotransporter,NKCC2,potassiumchloride cotransporter 2,S12A1,Slc12a1,sodium potassium chloride cotransporter 2,solute carrier family 12 (sodium/potassium/chloride transporters),Solute carrier family 12 member 1
Background: This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.
- 分子量
-
Observed_MW: 150kDa
Calculated_MW: 121kDa
- 基因ID
- 6557
- UniProt
- Q13621
-