我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

SLC12A1 抗体 (N-Term)

Name: SLC12A1 抗体 (N-Term)
SKU: ABIN2776780
Availability: OutOfStock

SLC12A1 适用: 大鼠, 人, 小鼠, 犬, Pig, 兔, 豚鼠, Cow, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-SLC12A1 Antibody Titration: 0. (SLC12A1 抗体 (N-Term))

Host: Rabbit Target Name: SLC12A1 Sample Type: Jurkat Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/lane Gel Concentration: 0. (SLC12A1 抗体 (N-Term))

Host: Rabbit Target Name: SLC12A1 Sample Tissue: Human A549 Antibody Dilution: 1. (SLC12A1 抗体 (N-Term))

Host: Rabbit Target Name: SLC12A1 Sample Tissue: Human THP-1 Whole Cell Antibody Dilution: 1ug/ml (SLC12A1 抗体 (N-Term))

Rabbit Anti-SLC12A1 Antibody Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (SLC12A1 抗体 (N-Term))

IHC

5 images

(3 references)

产品编号 ABIN2776780

发货至: 中国

Datasheet as PDF

抗原 See all SLC12A1 抗体

SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
抗原表位
11

3

2

2

2

1

1

1

1

1

1

1

1

1

1
N-Term
适用
26

24

13

6

2

2

2

1

1

1

1
大鼠, 人, 小鼠, 犬, Pig, 兔, 豚鼠, Cow, 马
宿主
37

2
兔
Compatible Secondaries
克隆类型
35

4
多克隆
标记
21

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This SLC12A1 antibody is un-conjugated
应用范围
32

24

10

5

5

3

3

3

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

NEKKSRGFFN YQASIFAENF GPRFTKGEGF FSVFAIFFPA ATGILAGANI

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against SLC12A1. It was validated on Western Blot and immunohistochemistry.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human SLC12A1
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) antibody
SLC12A1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibody
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 52-83), (N-Term) antibody
SLC12A1 适用: 大鼠, 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) antibody
SLC12A1 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 80-172) antibody
SLC12A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 351-400) antibody
SLC12A1 适用: 大鼠, 人, 小鼠, 猴, 犬, Pig, 兔, Cow, 马, Bat WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibody (HRP)
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal HRP

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibody (FITC)
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal FITC

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibody (Alkaline Phosphatase (AP))
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibody (Biotin)
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal Biotin

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 430 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Yoshioka, Kawaguchi, Nishimura, Akagi, Fujisawa, Yanagisawa, Matsumura, Tohyama: "Polyuria-associated hydronephrosis induced by xenobiotic chemical exposure in mice." in: American journal of physiology. Renal physiology, Vol. 311, Issue 4, pp. F752-F762, (2016) (PubMed).

Stec, Drummond, Gousette, Storm, Abraham, Csongradi: "Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 5, pp. 834-41, (2012) (PubMed).

Kelsen, Patel, Parker, Vera, Rimoldi, Gadepalli, Drummond, Stec: "Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells." in: American journal of physiology. Renal physiology, Vol. 295, Issue 4, pp. F1158-65, (2008) (PubMed).
抗原

SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))

别名

SLC12A1 (SLC12A1 产品)

别名

slc12a1 antibody, SLC12A1 antibody, DKFZp469A2020 antibody, BSC1 antibody, NKCC2 antibody, Nkcc2 antibody, AI788571 antibody, D630042G03Rik antibody, mBSC1 antibody, urehr3 antibody, si:ch211-220f12.1 antibody, solute carrier family 12 member 1 antibody, solute carrier family 12, member 1 antibody, si:ch211-220f12.1 antibody, SLC12A1 antibody, Slc12a1 antibody

背景

The sodium-potassium-chloride cotransporter isoform 2 is kidney-specific and is found on the apical membrane of the thick ascending limb of Henle's loop and the macula densa. It accounts for most of the NaCl resorption with the stoichiometry of 1Na:1K:2Cl and is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene.
Alias Symbols: BSC1, MGC48843, NKCC2
Protein Interaction Partner: STK39, OXSR1,
Protein Size: 430

分子量

47 kDa

基因ID

6557

NCBI登录号

NM_000338

UniProt

Q8IUN5