SLC12A1 抗体
(Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010].
recommended
SLC12A1 适用: 大鼠, 人, 小鼠, 犬, Pig, 兔, 豚鼠, Cow, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
recommended
recommended
SLC12A1 抗体 by 适用
Find SLC12A1 抗体 for a variety of species such as anti-Rat SLC12A1, anti-Human SLC12A1, anti-Mouse SLC12A1. The species listed below are among those available. Click on a link to go to the corresponding products.
SLC12A1 抗体 by 应用范围
Find SLC12A1 抗体 validated for a specific application such as WB, IHC, ELISA, ICC. Some of the available applications are listed below. Click on a link to go to the corresponding products.
SLC12A1 抗体 by 抗体来源
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SLC12A1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal SLC12A1 抗体. Click on a link to go to the corresponding products.
SLC12A1 抗体 by 克隆
Find SLC12A1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular SLC12A1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (3)
- (5)
Cat. No.
ABIN2776780
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7131078
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC
Validations
- (4)
- (2)
Cat. No.
ABIN863200
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN3043925
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (2)
Cat. No.
ABIN7075651
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN520255
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN6736611
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2486328
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2486327
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2486324
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2486326
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2486331
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2486325
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2486330
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN2486317
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SLC12A1 抗体
: "Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).: "Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma." in: Molecular cancer, Vol. 15, pp. 10, (2016) (PubMed).
: "Polyuria-associated hydronephrosis induced by xenobiotic chemical exposure in mice." in: American journal of physiology. Renal physiology, Vol. 311, Issue 4, pp. F752-F762, (2016) (PubMed).
: "Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model of Distal Nephron Salt Wasting." in: PLoS ONE, Vol. 11, Issue 7, pp. e0159804, (2016) (PubMed).
: "Regulation of the Na(+) -K(+) -2Cl(-) cotransporter by cGMP/cGMP-dependent protein kinase I after furosemide administration." in: The FEBS journal, (2015) (PubMed).
: "Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease." in: Scientific reports, Vol. 5, pp. 12480, (2015) (PubMed).
: "Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK." in: American journal of physiology. Renal physiology, Vol. 307, Issue 1, pp. F96-F106, (2014) (PubMed).
: "Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 5, pp. 834-41, (2012) (PubMed).
: "Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 11, pp. 1879-90, (2012) (PubMed).
: "Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells." in: American journal of physiology. Renal physiology, Vol. 295, Issue 4, pp. F1158-65, (2008) (PubMed).
Aliases for SLC12A1 抗体
si:ch211-220f12.1 (si:ch211-220f12.1) 抗体solute carrier family 12 member 1 (SLC12A1) 抗体
solute carrier family 12 member 1 (Slc12a1) 抗体
solute carrier family 12, member 1 (Slc12a1) 抗体
AI788571 抗体
BSC1 抗体
D630042G03Rik 抗体
DKFZp469A2020 抗体
mBSC1 抗体
NKCC2 抗体
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slc12a1 抗体
SLC12A1 抗体
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