SLC12A1 抗体
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北京 101111
Quick Overview for SLC12A1 抗体 (ABIN7131078)
抗原
See all SLC12A1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SLC12A1 Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of Human SLC12A1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
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别名
- SLC12A1
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背景
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Background: This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.
Aliases: BSC1 antibody, Bumetanide sensitive sodium 3 antibody, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 antibody, Kidney specific Na K Cl symporter antibody, Kidney-specific Na-K-Cl symporter antibody, MGC48843 antibody, Na K 2Cl cotransporter antibody, NKCC2 antibody, potassiumchloride cotransporter 2 antibody, S12A1_HUMAN antibody, Slc12a1 antibody, sodium potassium chloride cotransporter 2 antibody, solute carrier family 12 (sodium/potassium/chloride transporters) antibody, Solute carrier family 12 member 1 antibody
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UniProt
- Q13621
抗原
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