SKP2 抗体
(S-Phase Kinase-Associated Protein 2 (SKP2))
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class\; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2011].
recommended
SKP2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
SKP2 抗体 by 适用
Find SKP2 抗体 for a variety of species such as anti-Human SKP2, anti-Mouse SKP2, anti-Rat SKP2. The species listed below are among those available. Click on a link to go to the corresponding products.
SKP2 抗体 by 抗体来源
Find SKP2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
SKP2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal SKP2 抗体. Click on a link to go to the corresponding products.
SKP2 抗体 by 克隆
Find SKP2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular SKP2 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
- (5)
Cat. No.
ABIN737601
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, IF, ICC
Validations
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Cat. No.
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Datasheet
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
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Cat. No.
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Datasheet
Datasheet
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Datasheet
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Quantity
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Datasheet
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Datasheet
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Application
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Datasheet
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Reactivity
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Datasheet
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Latest Publications for our SKP2 抗体
: "S-phase kinase-associated protein 2 impairs the inhibitory effects of miR-1236-3p on bladder tumors." in: American journal of translational research, Vol. 10, Issue 3, pp. 731-743, (2018) (PubMed).: "Upregulation of Cdh1 Attenuates Isoflurane-Induced Neuronal Apoptosis and Long-Term Cognitive Impairments in Developing Rats." in: Frontiers in cellular neuroscience, Vol. 11, pp. 368, (2017) (PubMed).
: "RIG-I inhibits pancreatic β cell proliferation through competitive binding of activated Src." in: Scientific reports, Vol. 6, pp. 28914, (2016) (PubMed).
: "mTOR is involved in 17?-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1, and CCNE1." in: Molecular reproduction and development, Vol. 82, Issue 4, pp. 305-14, (2015) (PubMed).
: "MicroRNA-1285 regulates 17?-estradiol-inhibited immature boar Sertoli cell proliferation via adenosine monophosphate-activated protein kinase activation." in: Endocrinology, pp. en20141982, (2015) (PubMed).
: "Thyroid hormone inhibits the proliferation of piglet Sertoli cell via PI3K signaling pathway." in: Theriogenology, (2014) (PubMed).
: "The oncoprotein hepatitis B X-interacting protein promotes the migration of ovarian cancer cells through the upregulation of S-phase kinase-associated protein 2 by Sp1." in: International journal of oncology, Vol. 45, Issue 1, pp. 255-63, (2014) (PubMed).
: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, (2014) (PubMed).
: "Cdh1 inhibits reactive astrocyte proliferation after oxygen-glucose deprivation and reperfusion." in: Neurochemistry international, Vol. 63, Issue 2, pp. 87-92, (2013) (PubMed).
: "The oncoprotein HBXIP up-regulates Skp2 via activating transcription factor E2F1 to promote proliferation of breast cancer cells." in: Cancer letters, Vol. 333, Issue 1, pp. 124-32, (2013) (PubMed).
Aliases for SKP2 抗体
S-phase kinase-associated protein 2 (p45) (Skp2) 抗体S-phase kinase associated protein 2 (SKP2) 抗体
S-phase kinase associated protein 2 (Skp2) 抗体
FBL1 抗体
FBXL1 抗体
FLB1 抗体
p45 抗体
RGD1562456 抗体
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