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SKP2 抗体 (AA 156-185)

SKP2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19860 unconjugated
产品编号 ABIN652442
发货至: 中国
  • 抗原 See all SKP2 抗体
    SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
    抗原表位
    • 16
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 156-185
    适用
    • 70
    • 35
    • 33
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 62
    • 9
    • 1
    克隆类型
    • 61
    • 10
    多克隆
    标记
    • 41
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SKP2 antibody is un-conjugated
    应用范围
    • 50
    • 20
    • 18
    • 17
    • 14
    • 13
    • 13
    • 12
    • 12
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SKP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human SKP2.
    克隆位点
    RB19860
    亚型
    Ig Fraction
    Top Product
    Discover our top product SKP2 Primary Antibody
  • 应用备注
    WB: 1:1000. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
    别名
    SKP2 (SKP2 产品)
    别名
    FBXL1 antibody, FBL1 antibody, FLB1 antibody, p45 antibody, RGD1562456 antibody, S-phase kinase-associated protein 2 (p45) antibody, S-phase kinase associated protein 2 antibody, Skp2 antibody, SKP2 antibody
    背景
    SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class, in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas.
    分子量
    47761
    基因ID
    6502
    NCBI登录号
    NP_001230049, NP_005974, NP_116026
    UniProt
    Q13309
    途径
    Mitotic G1-G1/S Phases
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