IL-1 beta 抗体 (Internal Region)
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- 抗原 See all IL-1 beta (IL1B) 抗体
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-1 beta antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- IL1 beta Antibody detects endogenous levels of total IL1 beta.
- 预测反应
- Horse,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human IL1 beta, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product IL1B Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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Chronic lead exposure enhances the sympathoexcitatory response associated with P2X4 receptor in rat stellate ganglia." in: Environmental toxicology, Vol. 33, Issue 6, pp. 631-639, (2018) (PubMed).
: "Effects of Xin-Ji-Er-Kang on heart failure induced by myocardial infarction: Role of inflammation, oxidative stress and endothelial dysfunction." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 42, pp. 245-257, (2018) (PubMed).
: "Effects of Baicalin on Diabetic Cardiac Autonomic Neuropathy Mediated by the P2Y12 Receptor in Rat Stellate Ganglia." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 46, Issue 3, pp. 986-998, (2018) (PubMed).
: "miR-199b-5p Regulates Immune-Mediated Allograft Rejection after Lung Transplantation Through the GSK3β and NF-κB Pathways." in: Inflammation, Vol. 41, Issue 4, pp. 1524-1535, (2018) (PubMed).
: "Loss of NLRP3 Function Alleviates Murine Hepatic Graft-versus-Host Disease." in: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, (2018) (PubMed).
: "Involvement of P2Y12 receptor of stellate ganglion in diabetic cardiovascular autonomic neuropathy." in: Purinergic signalling, (2018) (PubMed).
: "Neuroprotective Effects of Resatorvid Against Traumatic Brain Injury in Rat: Involvement of Neuronal Autophagy and TLR4 Signaling Pathway." in: Cellular and molecular neurobiology, Vol. 37, Issue 1, pp. 155-168, (2017) (PubMed).
: "Rotenone Attenuates Renal Injury in Aldosterone-Infused Rats by Inhibiting Oxidative Stress, Mitochondrial Dysfunction, and Inflammasome Activation." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 3136-43, (2016) (PubMed).
: "Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury." in: International journal of molecular medicine, Vol. 37, Issue 4, pp. 921-30, (2016) (PubMed).
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Chronic lead exposure enhances the sympathoexcitatory response associated with P2X4 receptor in rat stellate ganglia." in: Environmental toxicology, Vol. 33, Issue 6, pp. 631-639, (2018) (PubMed).
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- 抗原
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- 别名
- IL1B (IL1B 产品)
- 别名
- IL-1 antibody, IL1-BETA antibody, IL1F2 antibody, IL-1BETA antibody, IL1beta antibody, il1-b antibody, zgc:111873 antibody, IL-1B antibody, IL-1beta antibody, Il-1b antibody, IL1B antibody, IL-1 beta antibody, IL-1b antibody, interleukin 1 beta antibody, interleukin 1, beta antibody, IL1B antibody, il1b antibody, Il1b antibody
- 背景
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Description: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
Gene: IL1B
- 分子量
- 30 kDa(precursor),17kDa(mature)
- 基因ID
- 3553
- UniProt
- P01584
- 途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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