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IL-1 beta 抗体 (AA 117-269)

IL1B 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5C3B7 unconjugated
产品编号 ABIN7193975
发货至: 中国
  • 抗原 See all IL-1 beta (IL1B) 抗体
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    抗原表位
    • 16
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    • 9
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    AA 117-269
    适用
    • 122
    • 87
    • 43
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    宿主
    • 175
    • 63
    • 6
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    • 2
    • 1
    小鼠
    克隆类型
    • 181
    • 74
    • 1
    单克隆
    标记
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    • 2
    • 2
    This IL-1 beta antibody is un-conjugated
    应用范围
    • 183
    • 106
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    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human IL1B (AA: 117-269) expressed in E. coli.
    克隆位点
    5C3B7
    亚型
    IgG1
    Top Product
    Discover our top product IL1B Primary Antibody
  • 应用备注
    WB:1:500 - 1:2000, ICC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,
    限制
    仅限研究用
  • 缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    别名
    IL1B (IL1B 产品)
    别名
    IL-1 antibody, IL1-BETA antibody, IL1F2 antibody, IL-1BETA antibody, IL1beta antibody, il1-b antibody, zgc:111873 antibody, IL-1B antibody, IL-1beta antibody, Il-1b antibody, IL1B antibody, IL-1 beta antibody, IL-1b antibody, interleukin 1 beta antibody, interleukin 1, beta antibody, IL1B antibody, il1b antibody, Il1b antibody
    背景

    Description: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase2 by this cytokine in the central nervous system is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

    Aliases: IL-1, IL1F2, IL1beta, IL1-BETA

    分子量
    30.7 kDa
    基因ID
    3553
    途径
    NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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