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- 抗原 See all CD137 (TNFRSF9) 抗体
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD137 antibody is conjugated to FITC
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应用范围
- ELISA, Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- CD137 Molecule of about 35 kd from activated T cells.
- 纯化方法
- Protein A purified
- 免疫原
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Ectodomain of recombinant human 4-1BB fusion protein.
Type of Immunogen: Fusion protein - 克隆位点
- 4B4-1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TNFRSF9 Primary Antibody
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- 应用备注
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Approved: ELISA, Flo, Func
Usage: Function: Blocks binding of CD137 huIg to Raji cells. Immobilized mAb induces TNF a production by monocytes. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze. Product is photosensitive and should be protected from light.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C. Do not freeze. Protect from light.
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CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 9, pp. 5042-51, (2001) (PubMed).
: "Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization." in: The Journal of biological chemistry, Vol. 271, Issue 25, pp. 14814-8, (1996) (PubMed).
: "How MAP kinases are regulated." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14843-6, (1995) (PubMed).
: "Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies." in: Cell regulation, Vol. 2, Issue 5, pp. 357-71, (1991) (PubMed).
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CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 9, pp. 5042-51, (2001) (PubMed).
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- 抗原
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
- 别名
- TNFRSF9 / 4-1BB / CD137 (TNFRSF9 产品)
- 别名
- TNFRSF9 antibody, zgc:136557 antibody, 4-1BB antibody, CD137 antibody, CDw137 antibody, ILA antibody, A930040I11Rik antibody, AA408498 antibody, AI325004 antibody, Cd137 antibody, Ly63 antibody, tumor necrosis factor receptor superfamily member 9 antibody, TNF receptor superfamily member 9 antibody, tumor necrosis factor receptor superfamily, member 9a antibody, tumor necrosis factor receptor superfamily, member 9 antibody, TNFRSF9 antibody, tnfrsf9a antibody, Tnfrsf9 antibody
- 背景
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Name/Gene ID: TNFRSF9
Family: TNF Receptor
Synonyms: TNFRSF9, 4-1BB ligand receptor, 4-1BB, CD137 antigen, CD137, Homolog of mouse 4-1BB, ILA, Receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CDw137 - 基因ID
- 3604
- UniProt
- Q07011
- 途径
- Cancer Immune Checkpoints
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