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CD137 抗体 (FITC)

TNFRSF9 适用: 人 ELISA, FACS, Func 宿主: 小鼠 Monoclonal 4B4-1 FITC
产品编号 ABIN610408
发货至: 中国
  • 抗原 See all CD137 (TNFRSF9) 抗体
    CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
    适用
    • 91
    • 38
    • 26
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    • 1
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    宿主
    • 45
    • 35
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    小鼠
    克隆类型
    • 53
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    单克隆
    标记
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    This CD137 antibody is conjugated to FITC
    应用范围
    • 65
    • 58
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    ELISA, Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    CD137 Molecule of about 35 kd from activated T cells.
    纯化方法
    Protein A purified
    免疫原
    Ectodomain of recombinant human 4-1BB fusion protein.

    Type of Immunogen: Fusion protein
    克隆位点
    4B4-1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TNFRSF9 Primary Antibody
  • 应用备注
    Approved: ELISA, Flo, Func

    Usage: Function: Blocks binding of CD137 huIg to Raji cells. Immobilized mAb induces TNF a production by monocytes. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze. Product is photosensitive and should be protected from light.
    储存条件
    4 °C
    储存方法
    Store at 4°C. Do not freeze. Protect from light.
  • Radoja, Saio, Schaer, Koneru, Vukmanovic, Frey: "CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 9, pp. 5042-51, (2001) (PubMed).

    Clark, Hynes: "Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization." in: The Journal of biological chemistry, Vol. 271, Issue 25, pp. 14814-8, (1996) (PubMed).

    Cobb, Goldsmith: "How MAP kinases are regulated." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14843-6, (1995) (PubMed).

    Boulton, Cobb: "Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies." in: Cell regulation, Vol. 2, Issue 5, pp. 357-71, (1991) (PubMed).

  • 抗原
    CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
    别名
    TNFRSF9 / 4-1BB / CD137 (TNFRSF9 产品)
    别名
    TNFRSF9 antibody, zgc:136557 antibody, 4-1BB antibody, CD137 antibody, CDw137 antibody, ILA antibody, A930040I11Rik antibody, AA408498 antibody, AI325004 antibody, Cd137 antibody, Ly63 antibody, tumor necrosis factor receptor superfamily member 9 antibody, TNF receptor superfamily member 9 antibody, tumor necrosis factor receptor superfamily, member 9a antibody, tumor necrosis factor receptor superfamily, member 9 antibody, TNFRSF9 antibody, tnfrsf9a antibody, Tnfrsf9 antibody
    背景
    Name/Gene ID: TNFRSF9
    Family: TNF Receptor

    Synonyms: TNFRSF9, 4-1BB ligand receptor, 4-1BB, CD137 antigen, CD137, Homolog of mouse 4-1BB, ILA, Receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CDw137
    基因ID
    3604
    UniProt
    Q07011
    途径
    Cancer Immune Checkpoints
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