CD137 抗体 (AA 150-250)
Our Local Distributor
北京 101111
Quick Overview for CD137 抗体 (AA 150-250) (ABIN7271073)
抗原
See all CD137 (TNFRSF9) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 150-250
-
原理
- 4-1BB/CD137 Rabbit pAb
-
序列
- GTKERDVVCG PSPADLSPGA SSVTPPAPAR EPGHSPQIIS FFLALTSTAL LFLLFFLTLR FSVVKRGRKK LLYIFKQPFM RPVQTTQEED GCSCRFPEEE E
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthetic peptide corresponding to a sequence within amino acids 150-250 of human 4-1BB/CD137 (NP_001552.2).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
-
别名
- TNFRSF9
-
背景
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.,TNFRSF9,4-1BB,CD137,CDw137,ILA,Cancer,Tumor immunology,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,CD markers,Cytokines,TNF,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Stem Cells,Hematopoietic Progenitors,TNFRSF9
-
分子量
- 27kDa
-
基因ID
- 3604
-
UniProt
- Q07011
-
途径
- Cancer Immune Checkpoints
抗原
-