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CD137 抗体 (AA 19-188)

TNFRSF9 适用: 人 ELISA, FACS, WB, IHC, IF, IHC (p), Coat, StM 宿主: 小鼠 Monoclonal 4-1BB-3201 unconjugated
产品编号 ABIN6939788
发货至: 中国
  • 抗原 See all CD137 (TNFRSF9) 抗体
    CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
    抗原表位
    • 16
    • 12
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-188
    适用
    • 91
    • 38
    • 26
    • 8
    • 4
    • 1
    • 1
    宿主
    • 45
    • 35
    • 11
    • 11
    • 2
    • 1
    小鼠
    克隆类型
    • 53
    • 47
    • 3
    单克隆
    标记
    • 59
    • 12
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD137 antibody is un-conjugated
    应用范围
    • 65
    • 57
    • 51
    • 12
    • 12
    • 11
    • 10
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Coating (Coat), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    A recombinant fragment (around aa 19-188) of human CD137 / 4-1BB / TNFRSF9 protein (exact sequence is proprietary)
    克隆位点
    4-1BB-3201
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TNFRSF9 Primary Antibody
  • 应用备注

    Positive Control: HEK293 cells, Jurkat whole cell lysate or recombinant human CD137 protein (WB). Human kidney cancer, liver, stomach or thyroid cancer tissue (IHC-P). Expressed on the surface of activated T- cells.

    Known Application: ELISA (For coating, order antibody without BSA), Immunofluorescence (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
    别名
    TNFRSF9 (TNFRSF9 产品)
    别名
    TNFRSF9 antibody, zgc:136557 antibody, 4-1BB antibody, CD137 antibody, CDw137 antibody, ILA antibody, A930040I11Rik antibody, AA408498 antibody, AI325004 antibody, Cd137 antibody, Ly63 antibody, tumor necrosis factor receptor superfamily member 9 antibody, TNF receptor superfamily member 9 antibody, tumor necrosis factor receptor superfamily, member 9a antibody, tumor necrosis factor receptor superfamily, member 9 antibody, TNFRSF9 antibody, tnfrsf9a antibody, Tnfrsf9 antibody
    背景
    CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.
    分子量
    32kDa (monomer), 85kDa (dimer)
    基因ID
    3604
    UniProt
    Q07011
    途径
    Cancer Immune Checkpoints
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