CD137 抗体 (AA 24-186)
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北京 101111
Quick Overview for CD137 抗体 (AA 24-186) (ABIN7092873)
抗原
See all CD137 (TNFRSF9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 24-186
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原理
- Anti-4-1BB antibody(DM66), Rabbit mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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免疫原
- Recombinant human 4-1BB (Leu24-Gln186) (ABIN6961084) produced by using human HEK293 cells
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亚型
- IgG
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应用备注
- ELISA 1:5000-10000, Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
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别名
- 4-1BB
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背景
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Synonyms:TNFRSF9, 4-1BB, CD137, CDw137, ILA
Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. -
分子量
- 27.9kDa
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基因ID
- 3604
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UniProt
- Q07011
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途径
- Cancer Immune Checkpoints
抗原
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