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NFKB1 抗体 (Ser337)
NFKB1
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC (p)
宿主: 兔
Polyclonal
unconjugated
NFKB1抗体详情
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抗原
See all NFKB1 抗体
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
抗原表位
All epitopes for NFKB1 抗体
Ser337
适用
All reactivities for NFKB1 抗体
人, 小鼠, 大鼠
宿主
All hosts for NFKB1 抗体
兔
克隆类型
All clonalities for NFKB1 抗体
多克隆
标记
All conjugates for NFKB1 抗体
This NFKB1 antibody is un-conjugated
应用范围
All applications for NFKB1 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
DKFZp686C01211,DNA binding factor KBF1,DNA binding factor KBF1 EBP1,DNA-binding factor KBF1,EBP 1,EBP-1,EBP1,KBF1,MGC54151,nf b,NF kappa B,NF kappaB,NF kappabeta,NF kB1,NFkappaB,NFKB 1,NFKB p105,NFKB p50,Nfkb1,NFKB1,Nuclear factor kappa B DNA binding subunit,Nuclear factor kappa-B,subunit 1,Nuclear factor NF kappa B p105 subunit,Nuclear factor NF kappa B p50 subunit,Nuclear factor NF-kappa-B p50 subunit,Nuclear factor of kappa light chain gene enhancer in B cells 1,Nuclear factor of kappa light polypeptide gene enhancer in B cells 1,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1,p105,p50,p84/NF-kappa-B1 p98,Transcription factor NFKB1
纯化方法
Affinity purification
免疫原
Synthesized peptide derived from human NFkappaB-p105/p50 around the non-phosphorylation site of S337.
亚型
IgG
Top Product
Discover our top product NFKB1 Primary Antibody
Alternatives
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使用细节
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应用备注
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
限制
仅限研究用
贮存及处理
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浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol pH 7.4.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
NFKB1目标详情
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抗原
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
别名
NFkappaB-p105/p50 (NFKB1 产品 )
别名
GKLP antibody, NKTL antibody, NTKL antibody, P105 antibody, TAPK antibody, TEIF antibody, TRAP antibody, EBP-1 antibody, KBF1 antibody, NF-kB1 antibody, NF-kappa-B antibody, NF-kappaB antibody, NFKB-p105 antibody, NFKB-p50 antibody, NFkappaB antibody, p105 antibody, p50 antibody, NF-kB antibody, NF-KB1 antibody, ebp-1 antibody, kbf1 antibody, nf-kappa-b antibody, nf-kappaB antibody, nfkb-p105 antibody, nfkb-p50 antibody, NF-kappaB1 antibody, p50/p105 antibody, BICDR-1 antibody, bicdr1 antibody, ccdc64 antibody, SCY1 like pseudokinase 1 antibody, nuclear factor kappa B subunit 1 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog antibody, nuclear factor NF-kappa-B p105 subunit antibody, nucleoporin 107 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody, SCYL1 antibody, NFKB1 antibody, Nfkb1 antibody, nfkb1.L antibody, CpipJ_CPIJ012236 antibody, Nup107 antibody, nfkb1 antibody
背景
NFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. This antibody can bind both p105 and p50 isoforms of NFKB1.
分子量
105kDa
基因ID
4790
UniProt
P19838
途径
p53 Pathway , NF-kappaB Signaling , RTK signaling , TCR Signaling , TLR signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Myometrial Relaxation and Contraction , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , S100 Proteins
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