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HRAS 抗体 (C-Term)
HRAS
适用: 人, 小鼠, 大鼠
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
HRAS抗体详情
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抗原
See all HRAS 抗体
HRAS
(HRas proto-oncogene, GTPase (HRAS))
抗原表位
All epitopes for HRAS 抗体
C-Term
适用
All reactivities for HRAS 抗体
人, 小鼠, 大鼠
宿主
All hosts for HRAS 抗体
兔
克隆类型
All clonalities for HRAS 抗体
多克隆
标记
All conjugates for HRAS 抗体
This HRAS antibody is un-conjugated
应用范围
All applications for HRAS 抗体
Western Blotting (WB), ELISA
特异性
N-RAS antibody is predicted to not cross-react with H-RAS
纯化方法
N-RAS Antibody is affinity chromatography purified via peptide column.
免疫原
N-RAS antibody was raised against a 15 amino acid peptide near the carboxy terminus of human N-RAS. The immunogen is located within the last 50 amino acids of N-RAS.
亚型
IgG
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使用细节
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应用备注
N-RAS antibody can be used for detection of N-RAS by Western blot at 1 and 2 μ,g/mL.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
N-RAS Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
N-RAS antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
HRAS目标详情
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抗原
HRAS
(HRas proto-oncogene, GTPase (HRAS))
别名
N-RAS (HRAS 产品 )
别名
C-BAS/HAS antibody, C-H-RAS antibody, C-HA-RAS1 antibody, CTLO antibody, H-RASIDX antibody, HAMSV antibody, HRAS1 antibody, K-RAS antibody, N-RAS antibody, RASH1 antibody, hras antibody, zgc:110250 antibody, HRAS antibody, H-RAS antibody, c-H-ras antibody, H-Ras antibody, K-Ras antibody, hras1 antibody, rash1 antibody, ras antibody, N-Ras antibody, c-bas/has antibody, H-ras antibody, Ha-ras antibody, Harvey-ras antibody, Hras-1 antibody, Kras2 antibody, c-Ha-ras antibody, c-rasHa antibody, hrasl antibody, zgc:110734 antibody, HRas proto-oncogene, GTPase antibody, v-Ha-ras Harvey rat sarcoma viral oncogene homolog a antibody, neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene antibody, Harvey rat sarcoma viral oncogene homolog L homeolog antibody, Harvey rat sarcoma viral oncogene homolog antibody, Harvey rat sarcoma virus oncogene antibody, NRAS proto-oncogene, GTPase antibody, -Ha-ras Harvey rat sarcoma viral oncogene homolog b antibody, HRAS antibody, hrasa antibody, LOC733587 antibody, Hras antibody, hras.L antibody, hras antibody, NRAS antibody, hrasb antibody
背景
N-RAS Antibody: Activating mutations and overexpression of classical Ras subfamily members (N-RAS, H-RAS, and K-RAS) have been widely investigated as key events in the development of human cancers. The N-RAS protein shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. N-RAS, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
分子量
Predicted: 22 kDa Observed: 22 kDa
基因ID
4893
NCBI登录号
NP_002515
UniProt
P01111
途径
p53 Pathway , MAPK Pathway , RTK signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Hepatitis C , Autophagy , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , Regulation of long-term Neuronal Synaptic Plasticity , VEGF Signaling , BCR Signaling
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