HRas proto-oncogene, GTPase 抗体
(HRas proto-oncogene, GTPase (HRAS))
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| HRAS 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant HRAS 抗体 (AA 50-100) | 人 | 兔 Monoclonal |
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| HRAS 抗体 (AA 104-128) | 人 | 兔 Polyclonal |
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| HRAS 抗体 | 人, 小鼠, 大鼠, 猴, 犬 | 小鼠 Monoclonal |
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| Recombinant HRAS 抗体 (AA 50-100) | 人, 小鼠 | 兔 Monoclonal |
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| Recombinant HRAS 抗体 | 人 | 兔 Monoclonal |
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| HRAS 抗体 | 人, 小鼠, 大鼠, 猴, 犬 | 小鼠 Monoclonal |
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| HRAS 抗体 (AA 104-128) | 人 | 兔 Polyclonal |
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| Recombinant HRAS 抗体 (AA 50-100) | 人 | 兔 Monoclonal |
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| HRAS 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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|
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| HRAS 抗体 | 人 | 小鼠 Monoclonal |
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| HRAS 抗体 (AA 146-176) | 人, 小鼠 | 兔 Polyclonal |
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| HRAS 抗体 | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| HRAS 抗体 (AA 1-189) | 人 | 兔 Polyclonal |
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| HRAS 抗体 | 人 | 兔 Monoclonal |
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| HRAS 抗体 (AA 12-181) | 人 | 兔 Polyclonal |
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| HRAS 抗体 (AA 2-186) | 大鼠 | 兔 Polyclonal |
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| HRAS 抗体 | 人 | 小鼠 Monoclonal |
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| HRAS 抗体 | 人 | 小鼠 Monoclonal |
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| HRAS 抗体 (AA 1-189) | 人 | 小鼠 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ICC (Immunocytochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
4 references - 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- BLR326M
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
- 抗原表位
- AA 50-100
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB15622
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 104-128
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴, 犬
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1C2
- 标记
- unconjugated
- 抗体亚型
- IgG2b
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- BLR341M
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
- 抗原表位
- AA 50-100
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 23GB6035
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴, 犬
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1A1
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 104-128
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- BLR326M
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
- 抗原表位
- AA 50-100
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB14565
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 146-176, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 146-176
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- H-Ras-03
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-189
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 12-181
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2-186
Primary Antibody
- WB (Western Blotting: 有验证图片)
- PLA (Proximity Ligation Assay: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-189
Latest Publications for our HRas proto-oncogene, GTPase 抗体
: "Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets." in: Cancer research, Vol. 78, Issue 4, pp. 891-908, (2019) (PubMed).
: "Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma." in: Oncotarget, Vol. 9, Issue 28, pp. 19753-19766, (2018) (PubMed).
: "Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells." in: Breast cancer research : BCR, Vol. 20, Issue 1, pp. 112, (2018) (PubMed).
: "Oncogenic HrasG12V expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma." in: PLoS ONE, Vol. 12, Issue 10, pp. e0186102, (2017) (PubMed).
: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).
: "Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines." in: Odontology / the Society of the Nippon Dental University, Vol. 100, Issue 2, pp. 149-55, (2012) (PubMed).
: "p66(Shc) restrains Ras hyperactivation and suppresses metastatic behavior." in: Oncogene, Vol. 29, Issue 41, pp. 5559-67, (2010) (PubMed).
: "The Hsp90 molecular chaperone: an open and shut case for treatment." in: The Biochemical journal, Vol. 410, Issue 3, pp. 439-53, (2008) (PubMed).
: "Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates ..." in: The FEBS journal, Vol. 274, Issue 17, pp. 4453-63, (2007) (PubMed).
: "Blind cavefish and heat shock protein chaperones: a novel role for hsp90alpha in lens apoptosis." in: The International journal of developmental biology, Vol. 48, Issue 8-9, pp. 731-8, (2004) (PubMed).
: "Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma." in: Oncotarget, Vol. 9, Issue 28, pp. 19753-19766, (2018) (PubMed).
: "Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells." in: Breast cancer research : BCR, Vol. 20, Issue 1, pp. 112, (2018) (PubMed).
: "Oncogenic HrasG12V expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma." in: PLoS ONE, Vol. 12, Issue 10, pp. e0186102, (2017) (PubMed).
: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).
: "Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines." in: Odontology / the Society of the Nippon Dental University, Vol. 100, Issue 2, pp. 149-55, (2012) (PubMed).
: "p66(Shc) restrains Ras hyperactivation and suppresses metastatic behavior." in: Oncogene, Vol. 29, Issue 41, pp. 5559-67, (2010) (PubMed).
: "The Hsp90 molecular chaperone: an open and shut case for treatment." in: The Biochemical journal, Vol. 410, Issue 3, pp. 439-53, (2008) (PubMed).
: "Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates ..." in: The FEBS journal, Vol. 274, Issue 17, pp. 4453-63, (2007) (PubMed).
: "Blind cavefish and heat shock protein chaperones: a novel role for hsp90alpha in lens apoptosis." in: The International journal of developmental biology, Vol. 48, Issue 8-9, pp. 731-8, (2004) (PubMed).
Aliases for HRas proto-oncogene, GTPase 抗体
HRas proto-oncogene, GTPase (HRAS) 抗体v-Ha-ras Harvey rat sarcoma viral oncogene homolog a (hrasa) 抗体
neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene (LOC733587) 抗体
HRas proto-oncogene, GTPase (Hras) 抗体
Harvey rat sarcoma viral oncogene homolog L homeolog (hras.L) 抗体
Harvey rat sarcoma viral oncogene homolog (hras) 抗体
Harvey rat sarcoma virus oncogene (Hras) 抗体
NRAS proto-oncogene, GTPase (NRAS) 抗体
resistance to audiogenic seizures (ras) 抗体
-Ha-ras Harvey rat sarcoma viral oncogene homolog b (hrasb) 抗体
asr 抗体
C-BAS/HAS 抗体
c-bas/has 抗体
C-H-RAS 抗体
c-H-ras 抗体
c-Ha-ras 抗体
C-HA-RAS1 抗体
c-rasHa 抗体
CTLO 抗体
H-RAS 抗体
H-Ras 抗体
H-ras 抗体
H-RASIDX 抗体
Ha-ras 抗体
HAMSV 抗体
Harvey-ras 抗体
hras 抗体
HRAS 抗体
Hras-1 抗体
HRAS1 抗体
hras1 抗体
hrasl 抗体
K-RAS 抗体
K-Ras 抗体
Kras2 抗体
N-RAS 抗体
N-Ras 抗体
ras 抗体
RASH1 抗体
rash1 抗体
zgc:110250 抗体
zgc:110734 抗体
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