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HRPT2 抗体

(Parafibromin (CDC73))
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009].
HRPT2 抗体  (AA 132-161) HRPT2 抗体  (AA 132-161) HRPT2 抗体 (AA 132-161) (ABIN653128)

CDC73 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB23239 unconjugated

HRPT2 抗体 HRPT2 抗体 HRPT2 抗体 (ABIN542414)

CDC73 适用: Drosophila melanogaster WB, ChIP 宿主: 兔 Polyclonal unconjugated

HRPT2 抗体  (AA 127-161) HRPT2 抗体  (AA 127-161) HRPT2 抗体 (AA 127-161) (ABIN6243752)

CDC73 适用: 人 WB 宿主: 兔 Polyclonal RB30818 unconjugated

HRPT2 抗体 by 适用

Find HRPT2 抗体 for a variety of species such as anti-Human HRPT2, anti-Mouse HRPT2, anti-Rat HRPT2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find HRPT2 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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HRPT2 抗体 by 抗原表位

Find HRPT2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

HRPT2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal HRPT2 抗体. Click on a link to go to the corresponding products.

HRPT2 抗体 by 克隆

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HRPT2 抗体 by 标记

Find HRPT2 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular HRPT2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, FACS, IHC (p)
Validations
  • (7)
Cat. No. ABIN653128
Quantity 400 μL
Datasheet Datasheet
Reactivity Drosophila melanogaster
Application WB, ChIP
Validations
  • (3)
  • (2)
Cat. No. ABIN542414
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243752
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7162615
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1679121
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN873005
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN901339
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN901334
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN901338
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN901329
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN2805083
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN901326
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN5008343
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN5008344
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN901340
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our HRPT2 抗体

Wu, Xu: "Histone H3R17me2a mark recruits human RNA polymerase-associated factor 1 complex to activate transcription." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 15, pp. 5675-80, (2012) (PubMed).

Yang, Han, Youn, Cho: "The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression." in: Nucleic acids research, Vol. 38, Issue 2, pp. 382-90, (2010) (PubMed).

Ruepp, Vivarelli, Pillai, Kleinschmidt, Azzouz, Barabino, Schümperli: "The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs." in: Nucleic acids research, Vol. 38, Issue 21, pp. 7637-50, (2010) (PubMed).

Rozenblatt-Rosen, Nagaike, Francis, Kaneko, Glatt, Hughes, LaFramboise, Manley, Meyerson: "The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 3, pp. 755-60, (2009) (PubMed).

Wang, Bowl, Bender, Peng, Farber, Chen, Ali, Zhang, Alberts, Thakker, Shilatifard, Williams, Teh: "Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice." in: Molecular and cellular biology, Vol. 28, Issue 9, pp. 2930-40, (2008) (PubMed).

Lin, Zhang, Panicker, Simonds: "The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 45, pp. 17420-5, (2008) (PubMed).

Tran, Hamada, Schwarz-Romond, Bienz: "Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains." in: Genes & development, Vol. 22, Issue 4, pp. 528-42, (2008) (PubMed).

Juhlin, Villablanca, Sandelin, Haglund, Nordenström, Forsberg, Bränström, Obara, Arnold, Larsson, Höög: "Parafibromin immunoreactivity: its use as an additional diagnostic marker for parathyroid tumor classification." in: Endocrine-related cancer, Vol. 14, Issue 2, pp. 501-12, (2007) (PubMed).

Mosimann, Hausmann, Basler: "Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo." in: Cell, Vol. 125, Issue 2, pp. 327-41, (2006) (PubMed).

Hoffmans, Basler: "BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling." in: Mechanisms of development, Vol. 124, Issue 1, pp. 59-67, (2006) (PubMed).

Aliases for HRPT2 抗体

cell division cycle 73 (CDC73) 抗体
cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73) 抗体
cell division cycle 73 (Cdc73) 抗体
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (cdc73) 抗体
cell division cycle 73 (cdc73) 抗体
parafibromin (Tsp_03925) 抗体
parafibromin (Tsp_04052) 抗体
parafibromin (Tsp_04125) 抗体
cell division cycle 73 S homeolog (cdc73.S) 抗体
8430414L16Rik 抗体
BC027756 抗体
C1orf28 抗体
C81219 抗体
C130030P16Rik 抗体
cdc73 抗体
HPTJT 抗体
HRPT2 抗体
Hrpt2 抗体
hrpt2 抗体
HYX 抗体
LOC100222932 抗体
MGC108428 抗体
zgc:63956 抗体
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