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NFKB1 抗体 (AA 905-909)
NFKB1
适用: 人
WB, IHC
宿主: 兔
Polyclonal
unconjugated
NFKB1抗体详情
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抗原
See all NFKB1 抗体
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
抗原表位
All epitopes for NFKB1 抗体
AA 905-909
适用
All reactivities for NFKB1 抗体
人
宿主
All hosts for NFKB1 抗体
兔
克隆类型
All clonalities for NFKB1 抗体
多克隆
标记
All conjugates for NFKB1 抗体
This NFKB1 antibody is un-conjugated
应用范围
All applications for NFKB1 抗体
Western Blotting (WB), Immunohistochemistry (IHC)
特异性
This antibody detects endogenous level of total NFκ,B-p105/p50 protein.
纯化方法
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
免疫原
NFkB-p105/p50 (Ab-907) antibody was raised against a peptide sequence around aa.905~909 (P-L-S-P-A) derived from Human NFκ,B-p105.
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使用细节
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应用备注
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store antibody at -20°C for up to one year.
NFKB1目标详情
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抗原
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
别名
NFkB p105 / p50 (NFKB1 产品 )
别名
GKLP antibody, NKTL antibody, NTKL antibody, P105 antibody, TAPK antibody, TEIF antibody, TRAP antibody, EBP-1 antibody, KBF1 antibody, NF-kB1 antibody, NF-kappa-B antibody, NF-kappaB antibody, NFKB-p105 antibody, NFKB-p50 antibody, NFkappaB antibody, p105 antibody, p50 antibody, NF-kB antibody, NF-KB1 antibody, ebp-1 antibody, kbf1 antibody, nf-kappa-b antibody, nf-kappaB antibody, nfkb-p105 antibody, nfkb-p50 antibody, NF-kappaB1 antibody, p50/p105 antibody, BICDR-1 antibody, bicdr1 antibody, ccdc64 antibody, SCY1 like pseudokinase 1 antibody, nuclear factor kappa B subunit 1 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog antibody, nuclear factor NF-kappa-B p105 subunit antibody, nucleoporin 107 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody, SCYL1 antibody, NFKB1 antibody, Nfkb1 antibody, nfkb1.L antibody, CpipJ_CPIJ012236 antibody, Nup107 antibody, nfkb1 antibody
背景
NF-κ,-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ,-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
分子量
120 kDa
基因ID
4790
NCBI登录号
NP_001158884
UniProt
P19838
途径
p53 Pathway , NF-kappaB Signaling , RTK signaling , TCR Signaling , TLR signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Myometrial Relaxation and Contraction , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , S100 Proteins
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