Insulin 抗体 (AA 1-84)
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- 抗原 See all Insulin (INS) 抗体
- Insulin (INS)
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抗原表位
- AA 1-84
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适用
- 人, Pig, Cow, 大鼠, 兔
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Insulin antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 产品特性
- This antibody cocktail recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. It enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Specific antibodies can be used as beta-cell and insulinoma markers.
- 纯化方法
- Protein G affinity chromatography
- 免疫原
- Full length purified pig Insulin (aa 1-84), clones E2-E3 and 2D11-H5, was used as the immunogen for this antibody cocktail.
- 克隆位点
- E2-E3-2D11-H5 or INS04-INS05
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product INS Primary Antibody
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anti-Insulin (INS) (AA 1-110) antibody
INS 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) (AA 46-59) antibodyINS 适用: 小鼠, 大鼠 ELISA, WB, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) antibodyINS 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Insulin (INS) (AA 90-110) antibodyINS 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) antibodyINS 适用: 人, Pig, 小鼠, Cow, 大鼠, 兔, 豚鼠, 犬, 猴, 山羊, Hamster, 马, 绵羊, Avian, Cat, 小鸡, 驴 WB 宿主: 山羊 Polyclonal unconjugated
anti-Insulin (INS) antibodyINS 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS 适用: 人 IHC, WB, IP, ICC 宿主: 小鼠 Monoclonal H10 unconjugated
anti-Insulin (INS) (AA 25-54) antibodyINS 适用: Cow IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
1. No special pretreatment is required for staining of formalin/paraffin tissues.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2) - 限制
- 仅限研究用
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- 浓度
- 0.2 mg/mL
- 缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store the Insulin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- 抗原
- Insulin (INS)
- 别名
- Insulin (INS 产品)
- 别名
- IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, ins1 antibody, xins antibody, ins1-a antibody, Insulin antibody, AA986540 antibody, Ins-2 antibody, InsII antibody, Mody antibody, Mody4 antibody, proinsulin antibody, zgc:109842 antibody, igf2-A antibody, ins antibody, ins-a antibody, ins-b antibody, insulin antibody, insulin precursor antibody, insulin II antibody, preproinsulin antibody, insulin L homeolog antibody, insulin S homeolog antibody, INS antibody, INS-IGF2 antibody, ins antibody, Ins antibody, PIN antibody, Ins2 antibody, ins.L antibody, ins.S antibody
- 背景
- This antibody cocktail recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. It enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Specific antibodies can be used as beta-cell and insulinoma markers.
- 基因ID
- 3630
- 途径
- NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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