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SLC12A1 抗体

(Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010].

44 results :

SLC12A1 适用: 人, 大鼠, 小鼠, 犬, Pig, 兔, 豚鼠, Cow, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
Pubmed 3 references
产品编号 ABIN2776780
 
SLC12A1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7131078
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
Pubmed 4 references
产品编号 ABIN863200
 
SLC12A1 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043925
 
SLC12A1 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7075651
 
SLC12A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated
产品编号 ABIN520255
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal HRP
产品编号 ABIN2486328
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal PerCP
产品编号 ABIN2486330
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal APC
产品编号 ABIN2486325
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal Atto 594
产品编号 ABIN2486319
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal Atto 488
产品编号 ABIN2486317
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal Atto 390
产品编号 ABIN2486316
 
SLC12A1 适用: 人, 大鼠, 小鼠, 猴, 犬, Pig, 兔, Cow, 马, Bat WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6736611
 
SLC12A1 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN632379
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal FITC
产品编号 ABIN2486327
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal Biotin
产品编号 ABIN2486326
 
SLC12A1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal PE
产品编号 ABIN2486331
 
SLC12A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6147841
 
SLC12A1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7270400
 
SLC12A1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1869474
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Immunocytochemistry (ICC)
    • Immunoprecipitation (IP)
    • Immunofluorescence (IF)
    • Confocal Microscopy (CM)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 适用
    • Human
    • Rat
    • Mouse
    • Monkey
    • Dog
    • Pig
    • Rabbit
    • Cow
    • Guinea Pig
    • Horse
    • Bat
  • 论文引用
  • 图像
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 4H4
    • 29S41
    • R07-5D1
  • 抗原表位
    • AA 33-55
    • AA 30-60
    • AA 52-83
    • AA 814-1099
    • C-Term
    • Cytoplasmic Domain
    • N-Term
    • AA 125-139
    • AA 351-400
    • AA 50-150
    • AA 776-790
    • AA 80-172
    • AA 80-173
    • Internal Region
    • Intracellular
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • APC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • Atto 390
    • Atto 488
    • Atto 594
    • HRP
    • PE
    • PerCP
  • 抗体亚型
    • IgG
    • IgG2a
    • IgG2a kappa
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Signalway
    • FabGennix
    • Boster Bio
    • USBio
    • Abbexa
    • Alomone Labs
    • Aviva Systems Biology
    • Biomatik
    • Cloud-Clone
    • ProSci

Latest Publications for our SLC12A1 抗体

Hyndman, Mironova, Giani, Dugas, Collins, McDonough, Stockand, Pollock: "Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Schrödter, Braun, Syring, Klümper, Deng, Schmidt, Perner, Müller, Ellinger: "Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma." in: Molecular cancer, Vol. 15, pp. 10, (2016) (PubMed).

Yoshioka, Kawaguchi, Nishimura, Akagi, Fujisawa, Yanagisawa, Matsumura, Tohyama: "Polyuria-associated hydronephrosis induced by xenobiotic chemical exposure in mice." in: American journal of physiology. Renal physiology, Vol. 311, Issue 4, pp. F752-F762, (2016) (PubMed).

Soleimani, Barone, Xu, Alshahrani, Brooks, McCormack, Smith, Zahedi: "Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model of Distal Nephron Salt Wasting." in: PLoS ONE, Vol. 11, Issue 7, pp. e0159804, (2016) (PubMed).

Limmer, Schinner, Castrop, Vitzthum, Hofmann, Schlossmann: "Regulation of the Na(+) -K(+) -2Cl(-) cotransporter by cGMP/cGMP-dependent protein kinase I after furosemide administration." in: The FEBS journal, (2015) (PubMed).

Zhang, Sun, Ding, Huang, Zhang, Jia: "Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease." in: Scientific reports, Vol. 5, pp. 12480, (2015) (PubMed).

Davies, Fraser, Galic, Choy, Katerelos, Gleich, Kemp, Mount, Power: "Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK." in: American journal of physiology. Renal physiology, Vol. 307, Issue 1, pp. F96-F106, (2014) (PubMed).

Stec, Drummond, Gousette, Storm, Abraham, Csongradi: "Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 5, pp. 834-41, (2012) (PubMed).

Toka, Al-Romaih, Koshy, DiBartolo, Kos, Quinn, Curhan, Mount, Brown, Pollak: "Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 11, pp. 1879-90, (2012) (PubMed).

Kelsen, Patel, Parker, Vera, Rimoldi, Gadepalli, Drummond, Stec: "Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells." in: American journal of physiology. Renal physiology, Vol. 295, Issue 4, pp. F1158-65, (2008) (PubMed).

Aliases for SLC12A1 抗体

si:ch211-220f12.1 (si:ch211-220f12.1) 抗体
solute carrier family 12 member 1 (SLC12A1) 抗体
solute carrier family 12 member 1 (Slc12a1) 抗体
solute carrier family 12, member 1 (Slc12a1) 抗体
AI788571 抗体
BSC1 抗体
D630042G03Rik 抗体
DKFZp469A2020 抗体
mBSC1 抗体
NKCC2 抗体
Nkcc2 抗体
slc12a1 抗体
SLC12A1 抗体
urehr3 抗体
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