SLC12A1 抗体
(Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010].
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44 results
SLC12A1
适用: 人, 大鼠, 小鼠, 猴, 犬, Pig, 兔, Cow, 马, Bat
WB, IHC
宿主: 兔
Polyclonal
unconjugated
2 images
Latest Publications for our SLC12A1 抗体
: "Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).: "Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma." in: Molecular cancer, Vol. 15, pp. 10, (2016) (PubMed).
: "Polyuria-associated hydronephrosis induced by xenobiotic chemical exposure in mice." in: American journal of physiology. Renal physiology, Vol. 311, Issue 4, pp. F752-F762, (2016) (PubMed).
: "Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model of Distal Nephron Salt Wasting." in: PLoS ONE, Vol. 11, Issue 7, pp. e0159804, (2016) (PubMed).
: "Regulation of the Na(+) -K(+) -2Cl(-) cotransporter by cGMP/cGMP-dependent protein kinase I after furosemide administration." in: The FEBS journal, (2015) (PubMed).
: "Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease." in: Scientific reports, Vol. 5, pp. 12480, (2015) (PubMed).
: "Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK." in: American journal of physiology. Renal physiology, Vol. 307, Issue 1, pp. F96-F106, (2014) (PubMed).
: "Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 5, pp. 834-41, (2012) (PubMed).
: "Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 11, pp. 1879-90, (2012) (PubMed).
: "Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells." in: American journal of physiology. Renal physiology, Vol. 295, Issue 4, pp. F1158-65, (2008) (PubMed).
Aliases for SLC12A1 抗体
si:ch211-220f12.1 (si:ch211-220f12.1) 抗体solute carrier family 12 member 1 (SLC12A1) 抗体
solute carrier family 12 member 1 (Slc12a1) 抗体
solute carrier family 12, member 1 (Slc12a1) 抗体
AI788571 抗体
BSC1 抗体
D630042G03Rik 抗体
DKFZp469A2020 抗体
mBSC1 抗体
NKCC2 抗体
Nkcc2 抗体
slc12a1 抗体
SLC12A1 抗体
urehr3 抗体
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