We are preparing the requested document. Please wait, this may take a while...!
|抗原||Met Proto-Oncogene (MET) 抗体|
|抗原表位||AA 208-407 其他选择|
|标记||This MET antibody is un-conjugated 其他选择|
Western Blotting (WB)
|Supplier||Log in to see|
MET抗体详情MET目标详情 使用细节 贮存及处理 References for anti-MET antibody (ABIN3042360) 图像
|原理||Rabbit IgG polyclonal antibody for Hepatocyte growth factor receptor(MET) detection. Tested with WB in Human,Rat.|
Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Rabbit IgG polyclonal antibody for Hepatocyte growth factor receptor(MET) detection. Tested with WB in Human,Rat.
Gene Name: MET proto-oncogene, receptor tyrosine kinase
Protein Name: Hepatocyte growth factor receptor
|纯化方法||Immunogen affinity purified.|
|免疫原||E.coli-derived human Met recombinant protein (Position: D208-S407). Human Met shares 90% and 91% amino acid (aa) sequences identity with mouse and rat Met, respectively.|
MET目标详情MET抗体详情 使用细节 贮存及处理 References for anti-MET antibody (ABIN3042360) 图像 回页首
|别名||MET (MET Antibody 摘要)|
C-Met, also called MET and hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. It is mapped to 7q31.2. The protein possesses tyrosine kinase activity. MET is a membrane receptor that is essential for embryonic development and wound healing. It induces several biological responses that collectively give rise to a program known as invasive growth. MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain. Normally, only stem cells and progenitor cells express MET, which allows these cells to grow invasively in order to generate new tissues in an embryo or regenerate damaged tissues in an adult. However, cancer stem cells are thought to hijack the ability of normal stem cells to express MET, and thus become the cause of cancer persistence and spread to other sites in the body.
Synonyms: AUTS9 antibody|c met antibody|c met antibody|cmet antibody|cmet antibody|D249 antibody|Hepatocyte growth factor receptor antibody|Hepatocyte growth factor receptor Precursor antibody|Hepatocyte growth factor receptor Precursor antibody|HGF antibody|HGF receptor antibody|HGF receptor antibody|HGF SF receptor antibody|HGF SF receptor antibody|HGF/SF receptor antibody|HGFR antibody|MET antibody|Met proto oncogene tyrosine kinase antibody|Met proto oncogene tyrosine kinase antibody|MET proto oncogene, receptor tyrosine kinase antibody|Met proto-oncogene (hepatocyte growth factor receptor) antibody|Met proto-oncogene antibody|Met protooncogene antibody|MET_HUMAN antibody|Oncogene MET antibody|Oncogene MET antibody|Par4 antibody|Proto-oncogene c-Met antibody|RCCP2 antibody|Renal cell carcinoma papillary 2 gene antibody|Renal cell carcinoma papillary 2 gene antibody|Scatter factor receptor antibody|SF receptor antibody|Tyrosine-protein kinase Met antibody
|途径||RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor|
使用细节MET抗体详情 MET目标详情 贮存及处理 References for anti-MET antibody (ABIN3042360) 图像 回页首
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for Met is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
贮存及处理MET抗体详情 MET目标详情 使用细节 References for anti-MET antibody (ABIN3042360) 图像 回页首
|溶解方式||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|缓冲液||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|注意事项||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|注意事项||Avoid repeated freezing and thawing.|
|储存条件||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
References for anti-MET antibody (ABIN3042360)MET抗体详情 MET目标详情 使用细节 贮存及处理 图像 回页首
Chen, Ding, Gao, Sun, Zhang, Du, Qiu, Wang, Zheng, Sun, Ni, Feng, Zhu: "A human anti-c-Met Fab fragment conjugated with doxorubicin as targeted chemotherapy for hepatocellular carcinoma." in: PLoS ONE, Vol. 8, Issue 5, pp. e63093, 2013
Bin, Ma, Xu, Shi: "Embryonic hepatocyte transplantation for hepatic cirrhosis: efficacy and mechanism of action." in: World journal of gastroenterology, Vol. 18, Issue 4, pp. 309-22, 2012
Chen, Wang, Guo, Yu, Burnstock, He, Xiang, Zheng: "Expression of P2Y(6) receptors in the developing mouse skeletal muscle and after injury and repair." in: Journal of anatomy, Vol. 218, Issue 6, pp. 643-51, 2011
图像MET抗体详情 MET目标详情 使用细节 贮存及处理 References for anti-MET antibody (ABIN3042360) 回页首