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c-MET 抗体 (AA 25-150)

Cited in 5+ publications. The 兔 多克隆 anti-c-MET antibody (ABIN671661) specifically detects c-MET in WB, IF, IHC (p) 和 IHC (fro). The antibody is reactive with 小鼠 samples.
产品编号 ABIN671661
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for c-MET 抗体 (AA 25-150) (ABIN671661)

抗原

See all c-MET (MET) 抗体
c-MET (MET) (Met Proto-Oncogene (MET))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This c-MET antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 25-150

    原理

    MET Polyclonal Antibody

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse MET

    亚型

    IgG
  • 应用备注

    WB(1:500-2000),

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Wang, Tang, Shen, Chen, Chen, Luo, Ge: "Hepatocyte growth factor (HGF) optimizes oral traumatic ulcer healing of mice by reducing inflammation." in: Cytokine, Vol. 99, pp. 275-280, (2018) (PubMed).

    Yu, He, Jiang, He, Fan, Wang, Geng, Dong: "Expression and tissue distribution of hepatocyte growth factor (HGF) and its receptor (c-Met) in alpacas (Vicugna pacos) skins associated with white and brown coat colors." in: Acta histochemica, (2015) (PubMed).

    Li, Zhang, Zhao, Shi, Yao, Zhang, Guo, Liu: "Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer." in: Oncology letters, Vol. 9, Issue 5, pp. 1989-1996, (2015) (PubMed).

    Gao, Bing, Li, Yang, Li, Chen: "Study of critical role of c-Met and its inhibitor SU11274 in colorectal carcinoma." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 2, pp. 546, (2013) (PubMed).

    Guo, Yang, Yao, Zhang, Da, Duan: "Expression of MACC1 and c-Met in human gastric cancer and its clinical significance." in: Cancer cell international, Vol. 13, Issue 1, pp. 121, (2013) (PubMed).

  • 抗原

    c-MET (MET) (Met Proto-Oncogene (MET))

    别名

    Met (c-Met)

    背景

    Synonyms: MET_HUMAN, Hepatocyte growth factor receptor, EC:2.7.10.1, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor(SF receptor), Tyrosine-protein kinase Met, MET proto-oncogene, receptor tyrosine kinase, DA11, HGFR, AUTS9, RCCP2, c-Met, c Met, DFNB97,

    Background: This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]

    基因ID

    4233

    UniProt

    P16056

    途径

    RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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