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SNCA 蛋白

SNCA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure SDS
产品编号 ABIN934870
发货至: 中国
  • 抗原 See all SNCA 蛋白
    SNCA (Synuclein, alpha (SNCA))
    蛋白类型
    Recombinant
    宿主
    • 25
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    资源
    • 26
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    • 3
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    大肠杆菌(E. Coli)
    应用范围
    SDS-PAGE (SDS)
    序列
    MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
    产品特性
    Purified recombinant Human alpha Synuclein protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.
    纯度
    > 95 % pure
    过滤
    0.2 μm filtered
    内毒素水平
    < 1.0 EU per µg of protein (determined by LAL method)
    Top Product
    Discover our top product SNCA 蛋白
  • 应用备注
    Alpha synuclein protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in sterile distilled water at a concentration of 1 mg/mL or less.
    浓度
    1 mg/mL
    缓冲液
    Lyophilized from a 0.2 µm filtered in 20 mM Tris-HCl buffer, pH 7.5, containing 100 mM NaCl, and 0 mM MgCl2.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    RT/-20 °C
    储存方法
    The product is shipped at ambient temperature. Upon receipt, store it immediately at 4 °C in the short term (1 month). For long term storage, aliquot and store at -20 °C or -70 °C.
  • 抗原
    SNCA (Synuclein, alpha (SNCA))
    别名
    alpha Synuclein (SNCA 产品)
    别名
    snca Protein, MGC64356 Protein, LOC619283 Protein, NACP Protein, alphaSYN Protein, PARK1 Protein, PARK4 Protein, PD1 Protein, synuclein alpha L homeolog Protein, alpha-synuclein Protein, synuclein alpha Protein, synuclein, alpha Protein, snca.L Protein, LOC619283 Protein, SNCA Protein, Snca Protein
    背景
    Alpha-Synuclein, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Moreover, recent studies have shown that alpha-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail (amino acids 96-140).
    Alternative Names: alphaSYN protein, SNCA protein, Non-A beta component of AD amyloid protein, PARK1 protein, , Non-A4 component of amyloid precursor protein, Synuclein alpha protein, MGC64356 protein, PARK 4 protein, Non-A-beta component of alzheimers disease amyloid protein, MGC127560 protein, Non A beta component of AD amyloid protein, Parkinson disease familial 1 protein, Non A4 component of amyloid precursor protein, alpha-Synuclein protein, MGC110988 protein, NACP protein, Alpha-synuclein isoform NACP140 protein, PD1 protein, precursor of PARK 1 protein, MGC105443 protein, Alpha synuclein protein, PD 1 protein, PARK4 protein
    分子量
    14.4 kDa (140 AA)
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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