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SNCA Protein (AA 1-139, partial) (GST tag)

SNCA 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant 90 % SDS, ELISA
产品编号 ABIN1046507
发货至: 中国
  • 抗原 See all SNCA 蛋白
    SNCA (Synuclein, alpha (SNCA))
    蛋白类型
    Recombinant
    产品特性
    AA 1-139, partial
    宿主
    • 24
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 25
    • 13
    • 3
    • 2
    大肠杆菌(E. Coli)
    标记
    This SNCA protein is labelled with GST tag.
    应用范围
    SDS-PAGE (SDS), ELISA
    序列
    MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPE
    产品特性
    May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
    纯度
    90 %
    Top Product
    Discover our top product SNCA 蛋白
  • 说明

    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS buffer, 20mM GSH
    储存条件
    -20 °C
  • Uéda, Saitoh, Mori: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).

    Campion, Martin, Heilig, Charbonnier, Moreau, Flaman, Petit, Hannequin, Brice, Frebourg: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).

    Uéda, Fukushima, Masliah, Xia, Iwai, Yoshimoto, Otero, Kondo, Ihara, Saitoh: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).

  • 抗原
    SNCA (Synuclein, alpha (SNCA))
    别名
    alpha-Synuclein (SNCA 产品)
    背景
    Synonyms: Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP
    分子量
    41.8 kD
    UniProt
    P37840
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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