SNCA Protein (His tag)
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- 抗原 See all SNCA 蛋白
- SNCA (Synuclein, alpha (SNCA))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This SNCA protein is labelled with His tag.
- 原理
- Recombinant Mouse α-Synuclein/SNCA Protein (His Tag)
- 序列
- Met1-Ala140
- 产品特性
- Recombinant Mouse alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SNCA 蛋白
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Synuclein, alpha (SNCA) (Ala53Thr-Mutant) (Active) protein
SNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) proteinSNCA 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)SNCA 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Synuclein, alpha (SNCA) (AA 1-140) protein (GST tag)SNCA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag)SNCA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (AA 1-139), (partial) protein (GST tag)SNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SNCA (Synuclein, alpha (SNCA))
- 别名
- alpha-Synuclein/SNCA (SNCA 产品)
- 别名
- snca Protein, MGC64356 Protein, LOC619283 Protein, NACP Protein, alphaSYN Protein, PARK1 Protein, PARK4 Protein, PD1 Protein, synuclein alpha L homeolog Protein, alpha-synuclein Protein, synuclein alpha Protein, synuclein, alpha Protein, snca.L Protein, LOC619283 Protein, SNCA Protein, Snca Protein
- 背景
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Background: Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's disease (PD) and Alzheimer's disease. Manyneurodegenerative diseases has shown that alpha-synuclein accumulates in dystrophic neurites and in Lewy bodies. The function of alpha-synuclein is closely correlated with its three-dimensional structure, especially for proteins important in the pathogenesis of neurodegenerative diseases. Alpha-synuclein is a dynamic molecule whose secondary structure depends on the environment. For example, it has an unfolded random coil structure in aqueous solution, forms a-helical structure upon binding to acidic phospholipid vesicles, and forms insoluble fibrils with a high b-sheet content that resemble the filaments found in Lewy bodies. Also, alpha-synuclein was known to associate with 14-3-3 proteins including protein kinase C, BAD, and extracellular regulated kinase, and overexpression of alpha-synuclein could contribute to cell death in neurodegenerative diseases.
Synonym: Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, Snca
- 分子量
- 15.9 kDa
- UniProt
- O55042
- 途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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