SNCA 蛋白
(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| SNCA Protein (full length) | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (A53T) | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (full length) | 小鼠 | 大肠杆菌（E. Coli） |
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| SNCA 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (AA 1-140) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| SNCA Protein (AA 1-140) (His-IF2DI Tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| SNCA Protein (active) | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (AA 31-140) (GST tag) | 人 | 小麦胚 |
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| SNCA Protein (AA 1-140) (GST tag) | 人 | 小麦胚 |
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| SNCA Protein (AA 1-140) | 小鼠 | 大肠杆菌（E. Coli） |
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| SNCA Protein (phosphorylated) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (AA 1-140) | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (AA 1-140) | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (AA 1-140) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| SNCA Protein (AA 1-140) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| SNCA Protein (A53T, AA 1-140) | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (AA 1-140, K23Q) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| SNCA Protein (AA 1-140) | 小鼠 | 大肠杆菌（E. Coli） |
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| SNCA 蛋白 | 人 | 大肠杆菌（E. Coli） |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- EM (Electron Microscopy: 有验证图片)
- WB (Western Blotting: 所列应用)
- in vitro (In vitro Assay: 所列应用)
- in vivo (In vivo Studies: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >95% pure using SDS-PAGE analysis.
- 生物活性
- Active
Protein
- IF (Immunofluorescence: 有验证图片)
- EM (Electron Microscopy: 有验证图片)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- in vitro (In vitro Assay: 所列应用)
- in vivo (In vivo Studies: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- EM (Electron Microscopy: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- in vitro (In vitro Assay: 所列应用)
- in vivo (In vivo Studies: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % pure
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 85 % as determined by SDS-PAGE.
Protein
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Latest Publications for our SNCA 蛋白
: "Unraveling the role of hydrogen peroxide in ?-synuclein aggregation using an ultrasensitive nanoplasmonic probe." in: Analytical chemistry, Vol. 87, Issue 3, pp. 1968-73, (2015) (PubMed).
: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).
: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).
: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).
: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).
: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).
: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).
: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).
: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).
Aliases for SNCA 蛋白
synuclein alpha L homeolog (snca.L) 蛋白alpha-synuclein (LOC619283) 蛋白
synuclein alpha (SNCA) 蛋白
synuclein, alpha (Snca) 蛋白
synuclein alpha (Snca) 蛋白
alphaSYN 蛋白
LOC619283 蛋白
MGC64356 蛋白
NACP 蛋白
PARK1 蛋白
PARK4 蛋白
PD1 蛋白
snca 蛋白
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