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Quick Overview for SNCA Protein (AA 1-140) (ABIN7320688)
抗原
See all SNCA 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 1-140
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原理
- Recombinant Mouse α-Synuclein/SNCA Protein
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序列
- Met1-Ala140
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产品特性
- Recombinant Mouse alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Immobilized Recombinant Mouse SNCA(PKSM041187) at 2μg/ml (100 μl/well) can bind AAnti-Human SNCA antibody.The ED50 of Anti-SNCA antibody is 4.65ng/ml.
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Synuclein, alpha (SNCA) (full length) (Active) protein
SNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (A53T) (Active) proteinSNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (AA 1-140) protein (GST tag)SNCA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag)SNCA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) proteinSNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)SNCA 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) (AA 1-140) protein (His-IF2DI Tag)SNCA 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) (active) proteinSNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS
Synuclein, alpha (SNCA) (AA 1-139), (partial) protein (GST tag)SNCA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- SNCA (Synuclein, alpha (SNCA))
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别名
- alpha-Synuclein/SNCA
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背景
- Alpha-synuclein,NACP,Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,Snca,Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).
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分子量
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Calculated MW: 14.5 kDa
Observed MW: 17 kDa
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基因ID
- 20617
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UniProt
- O55042
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途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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