MPL Protein (AA 26-482) (His tag)
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- 抗原 See all MPL 蛋白
- MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))
- 蛋白类型
- Recombinant
- 产品特性
- AA 26-482
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This MPL protein is labelled with His tag.
- 原理
- Mouse c-MPL/Thrombopoietin R Protein
- 序列
- Gln26-Trp482
- 产品特性
- Recombinant Mouse c-MPL/Thrombopoietin R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln26-Trp482.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product MPL 蛋白
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Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 26-491) protein (His tag)
MPL 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 26-635) protein (MBP tag,His tag)Crystallography grade MPL 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 1-635) protein (GST tag)MPL 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Myeloproliferative Leukemia Virus Oncogene (MPL) (AA 26-491) protein (His tag)MPL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Myeloproliferative Leukemia Virus Oncogene (MPL) protein (His tag)MPL 宿主: 大鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))
- 别名
- c-MPL (MPL 产品)
- 别名
- C-MPL Protein, CD110 Protein, MPLV Protein, THCYT2 Protein, TPOR Protein, TPO-R Protein, c-mpl Protein, c-mpl-I Protein, c-mpl-II Protein, hlb219 Protein, MPL Protein, mpll Protein, tpor Protein, tpor.b Protein, MPL proto-oncogene, thrombopoietin receptor Protein, myeloproliferative leukemia virus oncogene Protein, MPL Protein, Mpl Protein, mpl Protein
- 背景
- The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45 % of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.
- 分子量
- 52.3 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
- 途径
- JAK/STAT Signaling
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