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IL3RA Protein (AA 19-305) (Fc Tag)

IL3RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
产品编号 ABIN7274946
发货至: 中国
  • 抗原 See all IL3RA 蛋白
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    蛋白类型
    Recombinant
    产品特性
    AA 19-305
    宿主
    • 22
    • 8
    • 2
    • 1
    资源
    • 17
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL3RA protein is labelled with Fc Tag.
    原理
    Human IL-3 R alpha/CD123 Protein
    序列
    Thr19-Arg305
    产品特性
    Recombinant Human IL-3 R alpha/CD123 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr19-Arg305.
    纯度
    > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human IL-3, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-3 R alpha, hFc Tag with the EC50 of 42.7ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    别名
    IL-3 R alpha (IL3RA 产品)
    别名
    CD123 Protein, IL3R Protein, IL3RAY Protein, IL3RX Protein, IL3RY Protein, hIL-3Ra Protein, CDw123 Protein, SUT-1 Protein, Cyrl Protein, interleukin 3 receptor subunit alpha Protein, interleukin 3 receptor, alpha chain Protein, IL3RA Protein, Il3ra Protein
    背景
    Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias.
    分子量
    59.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
    途径
    JAK/STAT Signaling
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