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IL3RA Protein (AA 19-305) (His tag,AVI tag,Biotin)

IL3RA 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6973119
发货至: 中国
  • 抗原 See all IL3RA 蛋白
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 19-305
    宿主
    • 22
    • 8
    • 2
    • 1
    资源
    • 17
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL3RA protein is labelled with His tag,AVI tag,Biotin.
    特异性
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    产品特性
    Biotinylated Human IL-3 R alpha / CD123 Protein, His,Avitag™ (MALS verified)
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL3RA 蛋白
  • 应用备注
    MALS verified
    说明

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    别名
    IL-3 R alpha (IL3RA 产品)
    别名
    CD123 Protein, IL3R Protein, IL3RAY Protein, IL3RX Protein, IL3RY Protein, hIL-3Ra Protein, CDw123 Protein, SUT-1 Protein, Cyrl Protein, interleukin 3 receptor subunit alpha Protein, interleukin 3 receptor, alpha chain Protein, IL3RA Protein, Il3ra Protein
    背景
    Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
    分子量
    36.7 kDa
    NCBI登录号
    NP_002174
    途径
    JAK/STAT Signaling
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