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IL3RA Protein (Fc Tag)

IL3RA 宿主: Cynomolgus 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7321046
发货至: 中国
  • 抗原 See all IL3RA 蛋白
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    蛋白类型
    Recombinant
    宿主
    • 23
    • 8
    • 1
    • 1
    Cynomolgus
    资源
    • 18
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This IL3RA protein is labelled with Fc Tag.
    原理
    Recombinant Cynomolgus IL-3 Receptor Subunit Alpha/IL-3RA/CD123 (C-Fc)
    序列
    Arg18-Arg302
    产品特性
    Recombinant Cynomolgus Interleukin-3 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Arg18-Arg302 is expressed with a 6His tag at the C-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL3RA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    别名
    IL-3 Receptor Subunit Alpha/IL-3RA/CD123 (IL3RA 产品)
    别名
    CD123 Protein, IL3R Protein, IL3RAY Protein, IL3RX Protein, IL3RY Protein, hIL-3Ra Protein, CDw123 Protein, SUT-1 Protein, Cyrl Protein, interleukin 3 receptor subunit alpha Protein, interleukin 3 receptor, alpha chain Protein, IL3RA Protein, Il3ra Protein
    背景

    Background: CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors. CD123 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage-committed cells. CD123 is a heterodimer consisting of an alpha and a beta subunit. The alpha subunit alone binds IL-3 with low affinity. The beta subunit does not bind IL-3 by itself but is required for the high-affinity binding of IL-3 to the heterodimeric receptor complex.

    Synonym: Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123

    分子量
    33.6 kDa
    UniProt
    G8F3K3
    途径
    JAK/STAT Signaling
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