CTLA4 Protein (His tag)
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- 抗原 See all CTLA4 蛋白
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 豚鼠
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资源
- Yeast (Pichia pastoris)
- 标记
- This CTLA4 protein is labelled with His tag.
- 原理
- Recombinant Cavia porcellus CTLA-4/CD152 Protein (His Tag)
- 序列
- Ala37-Asp161
- 产品特性
- Recombinant Cavia porcellus CD152 is produced by our Yeast expression system and the target gene encoding Ala37-Asp161 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Mouse B7-1-Fc(Cat: PKSM041366) at 1μg/ml(100 μl/well) can bind Cavia porcellus CTLA-4-His. The ED50 of Cavia porcellus CTLA-4-His is 0.17ug/ml .
- Top Product
- Discover our top product CTLA4 蛋白
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Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) protein (Fc Tag)
CTLA4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) protein (mFc-His Tag)CTLA4 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA, FACS
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) protein (His tag)CTLA4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) protein (His-Avi Tag,Biotin)CTLA4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-160) protein (His tag)CTLA4 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) (Active) protein (His tag)CTLA4 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-160) (Active) protein (Fc Tag)CTLA4 宿主: 人 宿主: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE. Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-162) (Active) protein (His tag)CTLA4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) (Active) protein (Fc Tag,AVI tag,Biotin)CTLA4 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (Active) protein (His tag)CTLA4 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
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- 说明
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18-40 kDa
- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- 别名
- CTLA-4/CD152 (CTLA4 产品)
- 别名
- CTLA-4 Protein, CTLA4 Protein, CD152 Protein, Cd152 Protein, Ctla-4 Protein, Ly-56 Protein, CD Protein, CELIAC3 Protein, GRD4 Protein, GSE Protein, IDDM12 Protein, sCTLA4 Protein, cytotoxic T-lymphocyte associated protein 4 Protein, cytotoxic T-lymphocyte-associated protein 4 Protein, CTLA4 Protein, Ctla4 Protein
- 背景
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Background: Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
Synonym: Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4
- 分子量
- 14.1 kDa
- UniProt
- H0VUB1
- 途径
- Cancer Immune Checkpoints
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