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CTLA4 Protein (mFc-His Tag)

CTLA4 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA, FACS
产品编号 ABIN6961090
发货至: 中国
  • 抗原 See all CTLA4 蛋白
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    蛋白类型
    Recombinant
    宿主
    • 41
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    资源
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    HEK-293 Cells
    标记
    This CTLA4 protein is labelled with mFc-His Tag.
    应用范围
    ELISA, Flow Cytometry (FACS)
    原理
    Recombinant human CTLA-4 protein with C-terminal mouse Fc and 6xHis tag
    特异性
    CTLA-4 (Gln36-Ser161) mFc (Pro99-Lys330) 6xHis
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CTLA4 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    别名
    CTLA-4 (CTLA4 产品)
    别名
    CTLA-4 Protein, CTLA4 Protein, CD152 Protein, Cd152 Protein, Ctla-4 Protein, Ly-56 Protein, CD Protein, CELIAC3 Protein, GRD4 Protein, GSE Protein, IDDM12 Protein, sCTLA4 Protein, cytotoxic T-lymphocyte associated protein 4 Protein, cytotoxic T-lymphocyte-associated protein 4 Protein, CTLA4 Protein, Ctla4 Protein
    背景
    Synonymes: CTLA4, CD152
    Description: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
    分子量
    predicted molecular mass of 54 kDa after removal of the signal peptide.
    基因ID
    1493
    UniProt
    P16410
    途径
    Cancer Immune Checkpoints
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