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Sclerostin Protein (SOST) (His tag)

SOST 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318996
发货至: 中国
  • 抗原 See all Sclerostin (SOST) 蛋白
    Sclerostin (SOST)
    蛋白类型
    Recombinant
    宿主
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    资源
    • 9
    • 6
    • 3
    • 2
    • 1
    人细胞
    标记
    This Sclerostin protein is labelled with His tag.
    原理
    Recombinant Human Sclerostin/SOST Protein (His Tag)
    序列
    Gln24-Tyr213
    产品特性
    Recombinant Human Sclerostin is produced by our Mammalian expression system and the target gene encoding Gln24-Tyr213 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SOST 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 250 mM NaCl, pH 8.0.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Sclerostin (SOST)
    别名
    Sclerostin/SOST (SOST 产品)
    别名
    LOC100313724 Protein, CDD Protein, VBCH Protein, 5430411E23Rik Protein, sclerostin Protein, LOC100313724 Protein, SOST Protein, Sost Protein
    背景

    Background: Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

    Synonym: CDD,DAND6,SOST1,VBCH

    分子量
    22.3 kDa
    UniProt
    Q9BQB4
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