Sclerostin Protein (SOST) (His tag)
-
- 抗原 See all Sclerostin (SOST) 蛋白
- Sclerostin (SOST)
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This Sclerostin protein is labelled with His tag.
- 原理
- Recombinant Human Sclerostin/SOST Protein (His Tag)
- 序列
- Gln24-Tyr213
- 产品特性
- Recombinant Human Sclerostin is produced by our Mammalian expression system and the target gene encoding Gln24-Tyr213 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SOST 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 250 mM NaCl, pH 8.0.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- Sclerostin (SOST)
- 别名
- Sclerostin/SOST (SOST 产品)
- 别名
- LOC100313724 Protein, CDD Protein, VBCH Protein, 5430411E23Rik Protein, sclerostin Protein, LOC100313724 Protein, SOST Protein, Sost Protein
- 背景
-
Background: Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Synonym: CDD,DAND6,SOST1,VBCH
- 分子量
- 22.3 kDa
- UniProt
- Q9BQB4
-