Sclerostin 蛋白
(Sclerostin (SOST))
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Sclerostin Protein (SOST) (AA 24-213) (His-Avi Tag) | 人 | HEK-293 Cells |
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| Sclerostin Protein (SOST) (AA 24-213) (Biotin,His-Avi Tag) | 人 | HEK-293 Cells |
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| Sclerostin Protein (SOST) (AA 24-213, full length) (His tag) | 人 | Mammalian Cells |
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| Sclerostin Protein (SOST) (AA 69-258) (His tag) | Cynomolgus | HEK-293 Cells |
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| Sclerostin Protein (SOST) (His tag) | 大鼠 | HEK-293 Cells |
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| Sclerostin Protein (SOST) (AA 24-211) (His tag) | 小鼠 | HEK-293 Cells |
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| Sclerostin Protein (SOST) (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| Sclerostin Protein (SOST) (AA 24-213) (His tag) | 人 | 人细胞 |
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| Sclerostin Protein (SOST) (AA 24-211) (His tag) | 小鼠 | Mammalian Cells |
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| Sclerostin Protein (SOST) (AA 1-213) (His tag) | 人 | HEK-293 Cells |
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| Sclerostin Protein (SOST) (AA 24-213) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Sclerostin Protein (SOST) (AA 25-209) (His tag,GST tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| Sclerostin Protein (SOST) (AA 25-213) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Sclerostin Protein (SOST) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| Sclerostin Protein (SOST) (AA 25-213) (His tag) | 人 | HEK-293F Cells |
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| Sclerostin Protein (SOST) (AA 24-213) (His tag,Biotin) | 人 | HEK-293 Cells |
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| Sclerostin Protein (SOST) (AA 24-212) (His tag) | Cow | 酵母菌 |
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| Sclerostin Protein (SOST) (AA 29-213) (His tag) | 大鼠 | 酵母菌 |
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| Sclerostin Protein (SOST) (AA 24-213) (His tag) | Green Monkey | 酵母菌 |
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| Sclerostin Protein (SOST) (His-SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Tris-Bis PAGE
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- AcA (Activity Assay: 有验证图片)
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- 宿主
- 人
- 宿主
- 人细胞
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by SDS-PAGE.
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293F Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by reduced SDS-PAGE.
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Cow
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Green Monkey
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our Sclerostin 蛋白
: "Upregulated serum sclerostin level in the T2DM patients with femur fracture inhibits the expression of bone formation/remodeling-associated biomarkers via antagonizing Wnt signaling." in: European review for medical and pharmacological sciences, Vol. 21, Issue 3, pp. 470-478, (2017) (PubMed).
Aliases for Sclerostin 蛋白
sclerostin (LOC100313724) 蛋白sclerostin (SOST) 蛋白
sclerostin (Sost) 蛋白
5430411E23Rik 蛋白
CDD 蛋白
LOC100313724 蛋白
VBCH 蛋白
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