Prolactin Receptor Protein (PRLR) (Fc Tag)
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- 抗原 See all Prolactin Receptor (PRLR) 蛋白
- Prolactin Receptor (PRLR)
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This Prolactin Receptor protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse PRLR/Prolactin Receptor Protein (Fc Tag)
- 序列
- Gln20-Asp229
- 产品特性
- Recombinant Mouse Prolactin receptor is produced by our Mammalian expression system and the target gene encoding Gln20-Asp229 is expressed with a Fc tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PRLR 蛋白
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Prolactin Receptor (PRLR) (AA 25-234) protein (His tag)
PRLR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-236) protein (His tag)PRLR 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 20-229) protein (His tag)PRLR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-235) protein (Fc Tag)PRLR 宿主: 犬 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-234) (Active) protein (Fc Tag)PRLR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Prolactin Receptor (PRLR) (AA 25-234) (Active) protein (His tag)PRLR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Prolactin Receptor (PRLR) (AA 371-479) protein (GST tag)PRLR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Prolactin Receptor (PRLR) (AA 1-622) protein (GST tag)PRLR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Prolactin Receptor (PRLR) protein (His tag)PRLR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Prolactin Receptor (PRLR) protein (His tag,Fc Tag)PRLR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Prolactin Receptor (PRLR)
- 别名
- PRLR/Prolactin Receptor (PRLR 产品)
- 别名
- hPRLrI Protein, PRL-R Protein, prlr Protein, PRLRb Protein, PRLR Protein, tprlr Protein, DKFZp469D061 Protein, RATPRLR Protein, AI987712 Protein, Pr-1 Protein, Pr-3 Protein, Prlr-rs1 Protein, wu:fj65c07 Protein, prolactin receptor Protein, prolactin receptor L homeolog Protein, prolactin receptor S homeolog Protein, prolactin receptor a Protein, PRLR Protein, prlr.L Protein, prlr.S Protein, PR Protein, prlr Protein, Prlr Protein, prlra Protein
- 背景
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Background: The prolactin receptor (PRLR) is a member of the class I cytokine/lactogen receptor family which mediates the diverse cellular actions of prolactin in several tissues. PRLRs are expressed in normal and neoplastic human breast tissue, and in most breast cancer cells. PRLR contains an extracellular region that binds prolactin, a transmembrane region, and a cytoplasmatic region required for the activation of the Jak2-Stat5 signal transduction pathway by Prl which is essential for transcriptional activation of all known prolactin regulated genes. PRLRs have also been observed in ovarian follicular cells of mice, pigs, sheep, deer, and humans, as well as in luteal tissue in cow and horse ovaries. Furthermore, PRLR knockout mice exhibit failure of embryonic implantation, reduced number of mature oocytes, and low fertilization rates. Knockout females also display a reduced number of primary follicles.
Synonym: Prolactin receptor, PRL-R, Prlr, Prolactin R, PRLR
- 分子量
- 51.7 kDa
- UniProt
- Q08501
- 途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
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