Prolactin Receptor Protein (PRLR) (AA 25-234) (Fc Tag)
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- 抗原 See all Prolactin Receptor (PRLR) 蛋白
- Prolactin Receptor (PRLR)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 25-234
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Prolactin Receptor protein is labelled with Fc Tag.
- 序列
- AA 25-234
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.0 kDa. The protein migrates as 64 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PRLR 蛋白
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Prolactin Receptor (PRLR) (AA 25-234) protein (His tag)
PRLR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-236) protein (His tag)PRLR 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 20-229) protein (His tag)PRLR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-235) protein (Fc Tag)PRLR 宿主: 犬 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-234) (Active) protein (His tag)PRLR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Prolactin Receptor (PRLR) protein (Fc Tag)PRLR 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Prolactin Receptor (PRLR) (AA 371-479) protein (GST tag)PRLR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Prolactin Receptor (PRLR) (AA 1-622) protein (GST tag)PRLR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Prolactin Receptor (PRLR) protein (His tag)PRLR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Prolactin Receptor (PRLR) protein (His tag,Fc Tag)PRLR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- Prolactin Receptor (PRLR)
- 别名
- Prolactin R (PRLR 产品)
- 别名
- hPRLrI Protein, PRL-R Protein, prlr Protein, PRLRb Protein, PRLR Protein, tprlr Protein, DKFZp469D061 Protein, RATPRLR Protein, AI987712 Protein, Pr-1 Protein, Pr-3 Protein, Prlr-rs1 Protein, wu:fj65c07 Protein, prolactin receptor Protein, prolactin receptor L homeolog Protein, prolactin receptor S homeolog Protein, prolactin receptor a Protein, PRLR Protein, prlr.L Protein, prlr.S Protein, PR Protein, prlr Protein, Prlr Protein, prlra Protein
- 背景
- As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.
- 分子量
- 51.0 kDa
- NCBI登录号
- NP_000940
- 途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
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