JNK Protein (GST tag)
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- 抗原 See all JNK (MAPK8) 蛋白
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This JNK protein is labelled with GST tag.
- 原理
- Recombinant Human JNK1/MAPK8 Protein (GST Tag)
- 序列
- Met 1-Arg 427
- 产品特性
- A DNA sequence encoding the full length of human MAPK8 isoform JNK1 alpha 2 (NP_620637.1) (Met 1-Arg 427) was expressed with the GST tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MAPK8 蛋白
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Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-427) protein (GST tag)
MAPK8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 2-364) (Active) protein (GST tag)MAPK8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase 8 (MAPK8) (Lys55Met-Mutant) (Active) protein (GST tag)MAPK8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-384) (Active) proteinMAPK8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 2-383) protein (His tag)MAPK8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-427) protein (His tag)MAPK8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-384) protein (GST tag)MAPK8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 318-427) protein (GST tag)MAPK8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-384) protein (Strep Tag)Crystallography grade MAPK8 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-427) protein (Strep Tag)Crystallography grade MAPK8 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 25 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
- 别名
- JNK1/MAPK8 (MAPK8 产品)
- 别名
- JNK Protein, JNK-46 Protein, JNK1 Protein, JNK1A2 Protein, JNK21B1/2 Protein, PRKM8 Protein, SAPK1 Protein, SAPK1c Protein, AI849689 Protein, Prkm8 Protein, BSK Protein, BSK/DJNK Protein, Bsk Protein, CG5680 Protein, D-JNK Protein, D-junk Protein, DBSK/JNK Protein, DJNK Protein, DJNK/bsk Protein, Dmel\\CG5680 Protein, JNK/SAPK Protein, Jnk Protein, Junk Protein, SAPKa Protein, c-Jun Protein, dJNK Protein, jnk Protein, T10F20.15 Protein, jnk1 Protein, sapk1 Protein, mapk8 Protein, zgc:112379 Protein, JNKb Protein, mapk8b Protein, mitogen-activated protein kinase 8 Protein, Stress-activated protein kinase jnk-1 Protein, basket Protein, Protein kinase superfamily protein Protein, mitogen-activated protein kinase 8 L homeolog Protein, mitogen-activated protein kinase 8b Protein, mitogen-activated protein kinase 8B-like Protein, MAPK8 Protein, jnk-1 Protein, Mapk8 Protein, bsk Protein, ATMPK8 Protein, mapk8.L Protein, mapk8b Protein, LOC109094263 Protein
- 背景
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Background: Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The protein kinases JNK1 has been found to serve as critical molecular links between obesity, metabolic inflammation, and disorders of glucose homeostasis. It is critically involved in the promotion of diet-induced obesity, metabolic inflammation and beta-cell dysfunction. The selective deficiency of JNK1 in the murine nervous system is sufficient to suppress diet-induced obesity. Genetic analysis indicates that the effects of JNK1 can be separated from effects of JNK1 on obesity. JNK1 is a potential pharmacological target for the development of drugs that might be useful for the treatment of metabolic syndrome, and type 2 diabetes. Furthermore, JNK1 plays a major role in the hypoxic cellular damage. JNK1 protein might be an attractive target for antihypoxic therapy in increasing resistance to many pathological conditions and diseases, leading to the oxygen deficit.
Synonym: JNK,JNK-46,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1,SAPK1c
- 分子量
- 75 kDa
- NCBI登录号
- NP_620637
- 途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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