JNK 产品
(Mitogen-Activated Protein Kinase 8 (MAPK8))
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Featured JNK Categories
JNK 抗体
High quality antibodies with extensive validation data.
JNK ELISA试剂盒
Reliable ELISA kits for a wide range of species.
JNK 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended JNK 抗体
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Cat. No.
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Cat. No.
ABIN3020887
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse, Rabbit, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro)
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- (4)
Cat. No.
ABIN732368
Quantity
100 μL
Datasheet
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Cat. No.
ABIN519235
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100 μg
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Recommended JNK ELISA试剂盒
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Cat. No.
ABIN1981833
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96 tests
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Cat. No.
ABIN6968648
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96 tests
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ABIN2748302
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Recommended JNK 蛋白
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Cat. No.
ABIN1310303
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10 μg
Datasheet
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Reactivity
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Escherichia coli (E. coli)
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Cat. No.
ABIN5569846
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50 μg
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ABIN5570671
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Latest Publications for our JNK Products
: "MiR-377 promotes white adipose tissue inflammation and decreases insulin sensitivity in obesity via suppression of sirtuin-1 (SIRT1)." in: Oncotarget, Vol. 8, Issue 41, pp. 70550-70563, (2018) (PubMed).: "Dysifragilone A inhibits LPS‑induced RAW264.7 macrophage activation by blocking the p38 MAPK signaling pathway." in: Molecular medicine reports, Vol. 17, Issue 1, pp. 674-682, (2018) (PubMed).
: "Trimethylamine N-oxide promotes atherosclerosis via CD36-dependent MAPK/JNK pathway." in: Biomedicine & pharmacotherapy, Vol. 97, pp. 941-947, (2018) (PubMed).
: "Neuroprotective Effect of Modified Xijiao Dihuang Decoction against Oxygen-Glucose Deprivation and Reoxygenation-Induced Injury in PC12 Cells: Involvement of TLR4-MyD88/NF-κB Signaling Pathway." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 3848595, (2018) (PubMed).
: "The p75 neurotrophin receptor might mediate sepsis-induced synaptic and cognitive impairments." in: Behavioural brain research, Vol. 347, pp. 339-349, (2018) (PubMed).
: "Ferroptosis is newly characterized form of neuronal cell death in response to arsenite exposure." in: Neurotoxicology, Vol. 67, pp. 27-36, (2018) (PubMed).
: "Anti-inflammatory action of ambuic acid, a natural product isolated from the solid culture of Pestalotiopsis neglecta, through blocking ERK/JNK mitogen-activated protein kinase signaling pathway." in: Experimental and therapeutic medicine, Vol. 16, Issue 2, pp. 1538-1546, (2018) (PubMed).
: "Glucocorticoid mediates prenatal caffeine exposure-induced endochondral ossification retardation and its molecular mechanism in female fetal rats." in: Cell death & disease, Vol. 8, Issue 10, pp. e3157, (2018) (PubMed).
: "Pseudolaric acid B induced autophagy, but not apoptosis, in MRC5 human fibroblast cells." in: Oncology letters, Vol. 15, Issue 1, pp. 863-870, (2018) (PubMed).
: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).
Synonyms and alternative names related to JNK
mitogen-activated protein kinase 8 (MAPK8), Stress-activated protein kinase jnk-1 (jnk-1), mitogen-activated protein kinase 8 (Mapk8), basket (bsk), Protein kinase superfamily protein (ATMPK8), mitogen-activated protein kinase 8 L homeolog (mapk8.L), mitogen-activated protein kinase 8b (mapk8b), mitogen-activated protein kinase 8B-like (LOC109094263), AI849689, BSK, Bsk, BSK/DJNK, c-Jun, CG5680, D-JNK, D-junk, DBSK/JNK, DJNK, dJNK, DJNK/bsk, Dmel\\CG5680, JNK, Jnk, jnk, JNK-46, JNK/SAPK, JNK1, jnk1, JNK1A2, JNK21B1/2, JNKb, Junk, mapk8, mapk8b, PRKM8, Prkm8, SAPK1, sapk1, SAPK1c, SAPKa, T10F20.15, zgc:112379Protein level used designations for JNK
- JUN N-terminal kinase
- MAP kinase 8
- c-Jun N-terminal kinase 1
- mitogen-activated protein kinase 8 isoform JNK1 alpha1
- mitogen-activated protein kinase 8 isoform JNK1 beta2
- stress-activated protein kinase 1
- stress-activated protein kinase 1c
- JNK1 beta1 protein kinase
- MAPK 8
- mitogen activated protein kinase 8
- protein kinase mitogen-activated 8
- stress-activated protein kinase JNK1
- SAPK gamma
- c-jun NH2-terminal kinase
- p54 gamma
- CG5680-PB
- CG5680-PE
- CG5680-PF
- JNK
- JUN kinase
- Jun N-terminal kinase
- Jun NH2-terminal kinase
- Jun-N-terminal kinase
- Jun-kinase
- bsk-PB
- bsk-PE
- bsk-PF
- c-Jun N-terminal kinase
- c-Jun aminoterminal kinase
- c-Jun-N-terminal kinase
- drosophila JNK
- janus kinase 1
- jnk1a-1
- mitogen-activated protein kinase 8
- LOW QUALITY PROTEIN: mitogen-activated protein kinase 8B-like
- MAP kinase 8B
- MAPK 8B
- Mitogen-activated protein kinase 8B
- Stress-activated protein kinase JNKb
- c-Jun N-terminal kinase B
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