K-RAS 产品
(GTPase Kras (KRAS))
Categories
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008].
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Featured K-RAS Categories
K-RAS 抗体
High quality antibodies with extensive validation data.
K-RAS ELISA试剂盒
Reliable ELISA kits for a wide range of species.
K-RAS 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended K-RAS 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
- (5)
Cat. No.
ABIN561621
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (4)
Cat. No.
ABIN561622
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, FACS
Validations
- (7)
Cat. No.
ABIN3031120
Quantity
0.2 mL
Datasheet
Datasheet
Recommended K-RAS ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962518
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956365
Quantity
96 tests
Datasheet
Datasheet
Recommended K-RAS 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7319807
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667031
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123230
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our K-RAS Products
: "EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells." in: Acta pharmacologica Sinica, Vol. 41, Issue 2, pp. 270-277, (2020) (PubMed).: "Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations." in: Cancer research, Vol. 76, Issue 3, pp. 675-85, (2016) (PubMed).
: "Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." in: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).
: "Let-7a regulates mammosphere formation capacity through Ras/NF-κB and Ras/MAPK/ERK pathway in breast cancer stem cells." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 11, pp. 1686-97, (2015) (PubMed).
: "Evidence for aldosterone-dependent growth of renal cell carcinoma." in: International journal of experimental pathology, Vol. 95, Issue 4, pp. 244-50, (2014) (PubMed).
: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).
: "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. ..." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 5, pp. 1259-65, (2013) (PubMed).
: "4-Hydroxytamoxifen induces autophagic death through K-Ras degradation." in: Cancer research, Vol. 73, Issue 14, pp. 4395-405, (2013) (PubMed).
: "Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells." in: PLoS ONE, Vol. 7, Issue 12, pp. e51449, (2012) (PubMed).
: "Analysis of k-ras nuclear expression in fibroblasts and mesangial cells." in: PLoS ONE, Vol. 5, Issue 1, pp. e8703, (2010) (PubMed).
Synonyms and alternative names related to K-RAS
KRAS proto-oncogene, GTPase (KRAS), v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (kras), KRAS proto-oncogene, GTPase (Kras), Kirsten rat sarcoma viral oncogene homolog (Kras), semicolonial-7 (smco-7), Ras family protein (PGTG_03066), GTPase KRas (Tsp_02666), GTPase KRas (Tsp_01642), GTPase KRas (rask), Kirsten rat sarcoma viral oncogene homolog S homeolog (kras.S), AI929937, C-K-RAS, c-Ki-ras, CFC2, K-ras, k-ras, K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, Ki-ras, kras, Kras-2, kras-a, kras-b, KRAS1, Kras2, KRAS2, NS, NS3, p21, p21B, p21ras, ras, RASK2, rask2, wu:fa04e08, wu:fc14b12, wu:fc23g10, wu:fj89d12, zgc:85725Protein level used designations for K-RAS
- GTPase KRas
- fa04e08
- fc14b12
- fc23g10
- fj89d12
- xRAS2
- K-Ras 2
- Kirsten rat sarcoma viral oncogene homologue 2 (active)
- c-K-ras
- c-K-ras2 protein
- c-Kirsten-ras proto-oncogene
- ki-Ras
- v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
- K-ras p21 protein
- PR310 c-K-ras oncogene
- c-Ki-ras
- c-Kirsten-ras protein
- cellular c-Ki-ras2 proto-oncogene
- oncogene KRAS2
- transforming protein p21
- v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog
- Kirsten rat sarcoma oncogene 2, expressed
- p21 protein
- Kirsten rat sarcoma viral oncogene homolog S homeolog
- ras protein
- ras p21
- Kirsten rat sarcoma viral oncogene homolog
- Kirsten rat sarcoma viral (Kras-2) oncogene homolog
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