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Kallikrein 7 产品

(Kallikrein 7 (KLK7))

Categories

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011].

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Featured Kallikrein 7 Categories

Kallikrein 7 抗体

High quality antibodies with extensive validation data.

Kallikrein 7 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Kallikrein 7 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Kallikrein 7 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN948328
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
  • (3)
Cat. No. ABIN7477507
Quantity 1 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN2855653
Quantity 100 μL
Datasheet Datasheet

Recommended Kallikrein 7 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957256
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962041
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957257
Quantity 96 tests
Datasheet Datasheet

Recommended Kallikrein 7 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308870
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320700
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308869
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our Kallikrein 7 Products

Delaunay, Deschamps, Haddada, Walker, Soosaipillai, Soualmia, El Amri, Diamandis, Brattsand, Magdolen, Darmoul: "Aberrant expression of kallikrein-related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion." in: Molecular oncology, Vol. 11, Issue 10, pp. 1330-1347, (2018) (PubMed).

Sheets, Massey, Cronk, Iafrati, Herman: "Matrix- and plasma-derived peptides promote tissue-specific injury responses and wound healing in diabetic swine." in: Journal of translational medicine, Vol. 14, Issue 1, pp. 197, (2016) (PubMed).

McGovern, Meinert, de Veer, Hollier, Parker, Upton: "Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models." in: The British journal of dermatology, (2016) (PubMed).

Yu, Prassas, Dimitromanolakis, Diamandis: "Novel Biological Substrates of Human Kallikrein 7 Identified through Degradomics." in: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17762-75, (2015) (PubMed).

Yamamoto, Yamamoto, Yamada, Hasegawa, Hongo, Oda, Amizuka: "Hertwig's epithelial root sheath cell behavior during initial acellular cementogenesis in rat molars." in: Histochemistry and cell biology, Vol. 142, Issue 5, pp. 489-96, (2014) (PubMed).

Heiker, Klöting, Kovacs, Kuettner, Sträter, Schultz, Kern, Stumvoll, Blüher, Beck-Sickinger: "Vaspin inhibits kallikrein 7 by serpin mechanism." in: Cellular and molecular life sciences : CMLS, Vol. 70, Issue 14, pp. 2569-83, (2013) (PubMed).

Ishida-Yamamoto, Deraison, Bonnart, Bitoun, Robinson, OBrien, Wakamatsu, Ohtsubo, Takahashi, Hashimoto, Dopping-Hepenstal, McGrath, Iizuka, Richard, Hovnanian: "LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum." in: The Journal of investigative dermatology, Vol. 124, Issue 2, pp. 360-6, (2005) (PubMed).

Planque, de Monte, Guyetant, Rollin, Desmazes, Panel, Lemarié, Courty: "KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer." in: Biochemical and biophysical research communications, Vol. 329, Issue 4, pp. 1260-6, (2005) (PubMed).

Vasilopoulos, Cork, Murphy, Williams, Robinson, Duff, Ward, Tazi-Ahnini: "Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis." in: The Journal of investigative dermatology, Vol. 123, Issue 1, pp. 62-6, (2004) (PubMed).

Sumer, Ahmad, Al-Mouzan, Al-Awamy: "Interaction of alpha-thalassemia with other hemoglobinopathies in the eastern province of Saudi Arabia." in: Birth defects original article series, Vol. 23, Issue 5A, pp. 343-7, (1988) (PubMed).

Synonyms and alternative names related to Kallikrein 7

kallikrein related-peptidase 7 (chymotryptic, stratum corneum) (Klk7), kallikrein-related peptidase 7 (Klk7), kallikrein related peptidase 7 (KLK7), kallikrein related peptidase 7 (Klk7), hK7, Prss6, PRSS6, SCCE

Protein level used designations for Kallikrein 7

  • kallikrein 7 (chymotryptic, stratum corneum)
  • kallikrein-7
  • protease, serine, 6
  • serine protease 6
  • stratum corneum chymotryptic enzyme
  • thymopsin
  • kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
  • signal protein
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