KAT2A 产品
(K(lysine) Acetyltransferase 2A (KAT2A))
Categories
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009].
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Featured KAT2A Categories
Recommended KAT2A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (6)
Cat. No.
ABIN7260323
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (8)
Cat. No.
ABIN1679964
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN515990
Quantity
100 μg
Datasheet
Datasheet
Recommended KAT2A 蛋白
Product
Reactivity
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Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123656
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308356
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308354
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our KAT2A Products
: "H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis." in: Nature communications, Vol. 8, pp. 14799, (2017) (PubMed).: "Upregulation of KLF4 by methylseleninic acid in human esophageal squamous cell carcinoma cells: Modification of histone H3 acetylation through HAT/HDAC interplay." in: Molecular carcinogenesis, Vol. 54, Issue 10, pp. 1051-9, (2015) (PubMed).
: "A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease. ..." in: Human molecular genetics, Vol. 23, Issue 11, pp. 2995-3007, (2014) (PubMed).
: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).
: "Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 8, pp. 2703-8, (2007) (PubMed).
: "An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification." in: The Journal of biological chemistry, Vol. 281, Issue 1, pp. 20-6, (2006) (PubMed).
: "GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes." in: Gene, Vol. 347, Issue 1, pp. 83-97, (2005) (PubMed).
: "The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases." in: Oncogene, Vol. 23, Issue 14, pp. 2559-63, (2004) (PubMed).
: "Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter." in: The EMBO journal, Vol. 22, Issue 24, pp. 6550-61, (2003) (PubMed).
: "UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation." in: The EMBO journal, Vol. 20, Issue 12, pp. 3187-96, (2001) (PubMed).
Synonyms and alternative names related to KAT2A
K(lysine) acetyltransferase 2A (KAT2A), lysine acetyltransferase 2A (KAT2A), histone acetyltransferase KAT2A (LOC100176452), ras-related protein Rab-5C (LOC100597293), K(lysine) acetyltransferase 2A (Kat2a), lysine acetyltransferase 2A (Kat2a), 1110051E14Rik, AW212720, GCN5, Gcn5, GCN5L2, Gcn5l2, hGCN5, KAT2A, mmGCN5, PCAF-bProtein level used designations for KAT2A
- histone acetyltransferase KAT2A
- general control of amino acid synthesis 5-like 2
- GCN5 general control of amino-acid synthesis 5-like 2
- general control of amino acid synthesis protein 5-like 2
- K(lysine) acetyltransferase 2A
- GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2
- General control of amino acid synthesis, yeast, homolog-like 2
- STAF97
- histone acetyltransferase GCN5
- hsGCN5
- lysine acetyltransferase 2A
- GCN5 general control of amino acid synthesis-like 2
- PCAF-B/GCN5
- general control of amino acid synthesis, yeast homolog-like 2
- general control of amino acid synthesis-like 2
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