This SARS-CoV-2 Spike S1 protein is labelled with His tag.
原理
SARS-CoV-2 Spike S1, His Tag (BA.3/Omicron)
序列
Val 16 - Arg 685
特异性
SARS-CoV-2 Spike S1 (BA.3/Omicron)
产品特性
SARS-CoV-2 Spike S1, His Tag (BA.3/Omicron) (S1N-C52Hq) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1 (A67V,H69del,V70del,T95I,G142D,V143del,Y144del,Y145del,N211del,L212I,G339D,S371F,S373P,S375F,D405N,K417N,N440K,G446S,S477N,T478K,E484A,Q493R,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.3, GISAID clade: GRA, Nextstrain clade: 21M).
宿主: SARS Coronavirus-2 (SARS-CoV-2)
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
应用备注
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.5 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.
E2 Protein, Surface Glycoprotein Protein, S Protein
物质类
Viral Protein
背景
Synonyms: Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1, Description: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.