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SARS-CoV-2 Spike S1 Protein (BA.2.12.1 - Omicron) (His tag)

宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7273902
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike S1 蛋白
    SARS-CoV-2 Spike S1
    蛋白类型
    Recombinant
    产品特性
    BA.2.12.1 - Omicron
    宿主
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    SARS Coronavirus-2 (SARS-CoV-2)
    资源
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    HEK-293 Cells
    标记
    This SARS-CoV-2 Spike S1 protein is labelled with His tag.
    原理
    SARS-CoV-2 Spike S1 (Omicron BA.2.12.1) Protein
    序列
    Gln14-Arg683 (T19I, L24S, PPA25-27 del, G142D, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H)
    产品特性
    Recombinant SARS-CoV-2 Spike S1 (Omicron BA.2.12.1) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln14-Arg683(T19I, L24S, PPA25-27 del, G142D, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H).
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized SARS-CoV-2 Spike S1 (Omicron BA.2.12.1) , His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human ACE2, hFc Tag with the EC50 of 30.1ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product SARS-CoV-2 Spike S1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SARS-CoV-2 Spike S1
    Abstract
    SARS-CoV-2 Spike S1 产品
    别名
    E2 Protein, Surface Glycoprotein Protein, S Protein
    物质类
    Viral Protein
    背景
    The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    分子量
    76.05 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.
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