SARS-CoV-2 Spike S1 Protein (B.1.351 - beta, RBD) (His tag)
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- 抗原 See all SARS-CoV-2 Spike S1 蛋白
- SARS-CoV-2 Spike S1
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- B.1.351 - beta, RBD
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宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta
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资源
- HEK-293 Cells
- 标记
- This SARS-CoV-2 Spike S1 protein is labelled with His tag.
- 序列
- AA 319-537
- 特异性
- SARS-CoV-2 (COVID-19) S protein RBD (K417N, E484K, N501Y), His Tag (MALS verified)
- 产品特性
- SARS-CoV-2 S protein RBD (K417N, E484K, N501Y), His Tag is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (K417N, E484K, N501Y). K417N / E484K / N501Y mutations were identified in the SARS-CoV-2 variant (known as 20C/501Y.V2 or B.1.351 lineage) which emerged in South Africa.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike S1 蛋白
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- 应用备注
- MALS verified
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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An antigen microarray protocol for COVID-19 serological analysis." in: STAR protocols, Vol. 2, Issue 3, pp. 100815, (2021) (PubMed).
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An antigen microarray protocol for COVID-19 serological analysis." in: STAR protocols, Vol. 2, Issue 3, pp. 100815, (2021) (PubMed).
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- 抗原
- SARS-CoV-2 Spike S1
- 别名
- SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 产品)
- 别名
- E2 Protein, Surface Glycoprotein Protein, S Protein
- 物质类
- Viral Protein
- 背景
- It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- 分子量
- 26.6 kDa
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