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SARS-CoV-2 Spike S1 Protein (B.1.351 - beta, RBD) (His tag)

宿主: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN7013274
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike S1 蛋白
    SARS-CoV-2 Spike S1
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    B.1.351 - beta, RBD
    宿主
    • 95
    • 9
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    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta
    资源
    • 87
    • 6
    • 3
    • 3
    • 1
    • 1
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    HEK-293 Cells
    标记
    This SARS-CoV-2 Spike S1 protein is labelled with His tag.
    序列
    AA 319-537
    特异性
    SARS-CoV-2 (COVID-19) S protein RBD (K417N, E484K, N501Y), His Tag (MALS verified)
    产品特性
    SARS-CoV-2 S protein RBD (K417N, E484K, N501Y), His Tag is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (K417N, E484K, N501Y). K417N / E484K / N501Y mutations were identified in the SARS-CoV-2 variant (known as 20C/501Y.V2 or B.1.351 lineage) which emerged in South Africa.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SARS-CoV-2 Spike S1 蛋白
  • 应用备注
    MALS verified
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • Longworth, Dittmar: "An antigen microarray protocol for COVID-19 serological analysis." in: STAR protocols, Vol. 2, Issue 3, pp. 100815, (2021) (PubMed).

  • 抗原
    SARS-CoV-2 Spike S1
    别名
    SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 产品)
    别名
    E2 Protein, Surface Glycoprotein Protein, S Protein
    物质类
    Viral Protein
    背景
    It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    分子量
    26.6 kDa
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