SARS-CoV-2 Spike S1 Protein (B.1.351 - beta) (Fc Tag)
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- 抗原 See all SARS-CoV-2 Spike S1 蛋白
- SARS-CoV-2 Spike S1
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- B.1.351 - beta
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宿主
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta
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资源
- HEK-293 Cells
- 标记
- This SARS-CoV-2 Spike S1 protein is labelled with Fc Tag.
- 原理
- SARS-CoV-2 S1 protein (L18F, D80A, D215G, LAL242-244del, R246I, K417N, E484K, N501Y, D614G), Fc Tag
- 序列
- AA 16-685
- 产品特性
- SARS-CoV-2 S1 protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). The mutations (L18F, D80A, D215G, LAL242-244del, R246I, K417N, E484K, N501Y, D614G) were identified in the SARS-CoV-2 variant (known as B.1.351 or 20C/501Y.V2) which emerged in the South Africa.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike S1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- 储存条件
- -20 °C
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- 抗原
- SARS-CoV-2 Spike S1
- 别名
- SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 产品)
- 别名
- E2 Protein, Surface Glycoprotein Protein, S Protein
- 物质类
- Viral Protein
- 背景
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- 分子量
- 101.1 kDa
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