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TIM3 Protein (AA 22-202) (hIgG-His-tag)
TIM 3
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 85 % by SDS - PAGE.
SDS
产品细节
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抗原
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TIM3 (TIM 3)
(Hepatitis A Virus Cellular Receptor 2 (TIM 3))
蛋白类型
Recombinant
产品特性
AA 22-202
宿主
All origins for TIM3 蛋白
人
资源
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Baculovirus infected Insect Cells
标记
This TIM3 protein is labelled with hIgG-His-tag.
应用范围
SDS-PAGE (SDS)
序列
ADLSEVEYRA EVGQNAYLPC FYTPAAPGNL VPVCWGKGAC PVFECGNVVL RTDERDVNYW TSRYWLNGDF RKGDVSLTIE NVTLADSGIY CCRIQIPGIM NDEKFNLKLV IKPAKVTPAP TRQRDFTAAF PRMLTTRGHG PAETQTLGSL PDINLTQIST LANELRDSRL ANDLRDSGAT IRIGLEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH HHH
纯度
> 85 % by SDS - PAGE.
内毒素水平
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.5 mg/mL
缓冲液
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol
储存条件
4 °C,-20 °C,-80 °C
储存方法
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
目标详细情况
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抗原
TIM3 (TIM 3)
(Hepatitis A Virus Cellular Receptor 2 (TIM 3))
别名
HAVCR2 (TIM 3 产品 )
别名
HAVCR2 Protein, MGC140131 Protein, HAVcr-2 Protein, KIM-3 Protein, TIM3 Protein, TIMD-3 Protein, TIMD3 Protein, Tim-3 Protein, TIM-3 Protein, Tim3 Protein, Timd3 Protein, tim3 Protein, hepatitis A virus cellular receptor 2 Protein, HAVCR2 Protein, Havcr2 Protein
物质类
Virus
背景
HAVCR2, also known as hepatitis A virus cellular receptor 2, is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specificallyidentifies Th1 cells in both mice and human. It interactions with Galectin-9 can alternatively trigger immune stimulatory effects, such as the coactivation of NK cell cytotoxicity. Recombinant human HAVCR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
分子量
47.3kDa (423aa) 40-57kDa (SDS-PAGE under reducing conditions)
NCBI登录号
NP_116171
UniProt
Q8TDQ0
途径
Regulation of Lipid Metabolism by PPARalpha , Cancer Immune Checkpoints
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TIM3 蛋白
TIM3 Protein (AA 22-202) (hIgG-His-tag) (ABIN5854622)