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TIM3 Protein (mFc-His Tag)

TIM 3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
产品编号 ABIN6961103
发货至: 中国
  • 抗原 See all TIM3 (TIM 3) 蛋白
    TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
    蛋白类型
    Recombinant
    宿主
    • 25
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    • 1
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    资源
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    HEK-293 Cells
    标记
    This TIM3 protein is labelled with mFc-His Tag.
    应用范围
    ELISA
    原理
    Recombinant human TIM3 protein with C-terminal mouse Fc and 6xHis tag
    特异性
    TIM3 (Ser22-Gly202) mFc (Pro99-Lys330) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product TIM 3 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
    别名
    TIM3 (TIM 3 产品)
    别名
    HAVCR2 Protein, MGC140131 Protein, HAVcr-2 Protein, KIM-3 Protein, TIM3 Protein, TIMD-3 Protein, TIMD3 Protein, Tim-3 Protein, TIM-3 Protein, Tim3 Protein, Timd3 Protein, tim3 Protein, hepatitis A virus cellular receptor 2 Protein, HAVCR2 Protein, Havcr2 Protein
    物质类
    Virus
    背景
    Synonymes: HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
    Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
    分子量
    predicted molecular mass of 47.5 kDa after removal of the signal peptide.
    基因ID
    84868
    UniProt
    Q8TDQ0
    途径
    Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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