TIM3 Protein (AA 22-200) (His tag,AVI tag,Biotin)
(1 reference)-
- 抗原 See all TIM3 (TIM 3) 蛋白
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 22-200
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TIM3 protein is labelled with His tag,AVI tag,Biotin.
- 品牌
- PrecisionAvi
- 序列
- AA 22-200
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 产品特性
- This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 23.1 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product TIM 3 蛋白
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Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-200) protein (His tag)
TIM 3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-200) protein (His-Avi Tag,Biotin)TIM 3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-191) protein (His tag)TIM 3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatitis A Virus Cellular Receptor 2 (TIM 3) protein (mFc-His Tag)TIM 3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Hepatitis A Virus Cellular Receptor 2 (TIM 3) protein (His tag)TIM 3 宿主: Marmoset 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 20-191) protein (His tag)TIM 3 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (Active) protein (Fc Tag)TIM 3 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 20-193) protein (His tag)TIM 3 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Hepatitis A Virus Cellular Receptor 2 (TIM 3) protein (Fc Tag)TIM 3 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 1-142) protein (GST tag)TIM 3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
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: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
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- 抗原
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 别名
- TIM-3 (TIM 3 产品)
- 别名
- HAVCR2 Protein, MGC140131 Protein, HAVcr-2 Protein, KIM-3 Protein, TIM3 Protein, TIMD-3 Protein, TIMD3 Protein, Tim-3 Protein, TIM-3 Protein, Tim3 Protein, Timd3 Protein, tim3 Protein, hepatitis A virus cellular receptor 2 Protein, HAVCR2 Protein, Havcr2 Protein
- 物质类
- Virus
- 背景
- Hepatitis A virus cellular receptor 2 is also known as HAVCR2, FLJ14428, KIM3, TIM3, TIMD3, is a member of the TIM family of immune regulating molecules with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. HAVCR2 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. HAVCR2 regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Dysregulation of the HAVCR2-galectin-9 pathway could underlie chronic autoimmune disease states in human, such as multiple sclerosis.
- 分子量
- 23.1 kDa
- NCBI登录号
- NP_116171
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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