IL12RB1 Protein (AA 24-545) (His tag)
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- 抗原 See all IL12RB1 蛋白
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-545
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This IL12RB1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- CRTSECCFQD PPYPDADSGS ASGPRDLRCY RISSDRYECS WQYEGPTAGV SHFLRCCLSS GRCCYFAAGS ATRLQFSDQA GVSVLYTVTL WVESWARNQT EKSPEVTLQL YNSVKYEPPL GDIKVSKLAG QLRMEWETPD NQVGAEVQFR HRTPSSPWKL GDCGPQDDDT ESCLCPLEMN VAQEFQLRRR QLGSQGSSWS KWSSPVCVPP ENPPQPQVRF SVEQLGQDGR RRLTLKEQPT QLELPEGCQG LAPGTEVTYR LQLHMLSCPC KAKATRTLHL GKMPYLSGAA YNVAVISSNQ FGPGLNQTWH IPADTHTEPV ALNISVGTNG TTMYWPARAQ SMTYCIEWQP VGQDGGLATC SLTAPQDPDP AGMATYSWSR ESGAMGQEKC YYITIFASAH PEKLTLWSTV LSTYHFGGNA SAAGTPHHVS VKNHSLDSVS VDWAPSLLST CPGVLKEYVV RCRDEDSKQV SEHPVQPTET QVTLSGLRAG VAYTVQVRAD TAWLRGVWSQ PQRFSIEVQV SDHHHHHH
- 纯度
- > 85 % by SDS - PAGE.
- 内毒素水平
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product IL12RB1 蛋白
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Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) protein (His tag)
IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (Fc Tag,AVI tag,Biotin)IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) protein (GST tag)IL12RB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (His tag)IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (Fc Tag)IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- Liquid. In phosphate buffered saline ( pH 7.4) containing 30 % glycerol, 1 mM EDTA, 0.1 mM PMSF.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- 别名
- IL12RB1 (IL12RB1 产品)
- 别名
- Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein
- 背景
- IL12RB1, also known as Interleukin-12 receptor subunit beta-1, is a intercellular adhesion molecule 1. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. It forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this protein and IL12RB2 was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Recombinant human IL12RB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- 分子量
- 58.4kDa (528aa) 50-70kDa (SDS-PAGE under reducing conditions.)
- NCBI登录号
- NP_005526
- UniProt
- P42701
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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