IL12RB1 Protein (AA 24-540) (Fc Tag,AVI tag,Biotin)
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- 抗原 See all IL12RB1 蛋白
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 24-540
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL12RB1 protein is labelled with Fc Tag,AVI tag,Biotin.
- 序列
- AA 24-540
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 纯度
- >95 % as determined by reduced SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product IL12RB1 蛋白
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Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) protein (His tag)
IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) protein (GST tag)IL12RB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 592-738) protein (His tag)Crystallography grade IL12RB1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 20-565) protein (His tag)Crystallography grade IL12RB1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-662) protein (rho-1D4 tag)Crystallography grade IL12RB1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 20-738) protein (rho-1D4 tag)Crystallography grade IL12RB1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (His tag)IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (Fc Tag)IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- 别名
- IL-12 R beta 1 (IL12RB1 产品)
- 别名
- Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein
- 背景
- The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
- 分子量
- 85.3 kDa
- NCBI登录号
- NP_005526
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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